Recombinant Human CD84 Protein (His tag) 100µg
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Catalog number
PKSH031880-100µg
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Price
Please ask
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Size
100µg
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Synonym
hCD84;LY9B;mCD84;SLAMF5
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Activity
NA
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Sequence
Met 1-Gly 225
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Fusion tag
C-His
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Accession
NP_003865.1
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Expressed Host
HEK293 Cells
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Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity
>95 % as determined by SDS-PAGE
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Endotoxin
<1.0 EU per µg as determined by the LAL method
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Stability and Storage
Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass
24 kDa
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AP Mol Mass
45 kDa
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Formulation
Lyophilized from sterile PBS, pH 7.4
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Reconstitution
Please refer to it for detailed information.
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Background
The CD2 family receptors are type I transmembrane glycoproteins belonging to immunoglobulin (Ig) superfamily characterized by a membrane-proximal Ig constant 2 (C2) domain and a membrane-distal variable (V) domain that is responsible for ligand recognition. CD84, also known as LY9B and SLAMF5, is a homophilic member of the SLAM (signaling lymphocyte activation molecule) subfamily of the CD2 family. The SLAM family receptorsmediate signal transduction through the interaction of its ITSM (immunoreceptor tyrosine-based switch motifs) in the intracellular region and the SH2 domain of adaptor molecules SAP (SLAM-associated protein) and EAT-2 (EWS-activated transcript 2), and accordingly modulate both adaptive and innate immune responses. The CD84-CD84 interaction was independent of its cytoplasmic tail. Thus, CD84 is its own ligand and acts as a costimulatory molecule. CD84 is expressed on cells from almost all hematopoietic lineages and on CD34+ hematopoietic progenitor cells, suggesting that CD84 serves as a marker for committed hematopoietic progenitor cells.
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Conjugation
histidine
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
CD84, SLAMF9
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Short name
Recombinant CD84 Protein (His tag) 100µg
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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Label
His
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Species
Human, Humans
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Alternative name
Rec. H. sapiens CD84 molecule Protein (histidine detection labelled) 100µg
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Alternative technique
rec
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Alternative to gene target
CD84 molecule, hCD84 and LY9B and mCD84 and SLAMF5, CD84 and IDBG-104060 and ENSG00000066294 and 8832, protein binding, Plasma membranes, Cd84 and IDBG-204869 and ENSMUSG00000038147 and 12523, CD84 and IDBG-630532 and ENSBTAG00000019033 and
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Gene info
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Identity
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Gene
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Long gene name
CD84 molecule
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Synonyms gene name
- CD84 antigen (leukocyte antigen)
- CD84 molecule
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Synonyms
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GenBank acession
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Locus
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Discovery year
1999-01-18
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Ig-like cell adhesion molecule family
- Immunoglobulin like domain containing
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
SLAM family member 9
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Synonyms
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GenBank acession
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Locus
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Discovery year
2003-10-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Product images
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