Recombinant Human CASP3 / Caspase-3 / CASP-3 Protein (His Tag)

Protein category

Recombinant protein
Source

E. coli
Target

CADSP3 / Caspase-3 / CASP-3 Protein
Recombinants
Description

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
Conjugation

histidine
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source

Recombinants or rec. proteins
Group

recombinants

Gene target

CASP3 Caspase-3 CASP-3 Protein His Tag
Gene symbol

CASP3, CRTAP, CASP8, MIR1302-3, MIR509-3, MIR7-3, PIRC14, PIRC12
Short name

Recombinant CASP3 / Caspase-3 / CASP-3 Protein (His Tag)
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. adv advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
Label

His tag
Species

Human, Humans
Alternative name

Rec. H. sapiens caspase 3, apoptosis-related cysteine peptidase / caspase-3 / caspase-3 Protein (histidine detection labelled)
Alternative technique

rec
Alternative to gene target

caspase 3, apoptosis-related cysteine peptidase, CPP32 and CPP32B and SCA-1, CASP3 and IDBG-46394 and ENSG00000164305 and 836, cysteine-type endopeptidase activity involved in execution phase of apoptosis, nuclei, Casp3 and IDBG-154306 and ENSMUSG00000031628 and 12367, CASP3 and IDBG-628521 and ENSBTAG00000015874 and 408016

Identity

HGNC:1504
Gene

CASP3
Long gene name

caspase 3
Synonyms gene name
- caspase 3, apoptosis-related cysteine protease
- caspase 3, apoptosis-related cysteine peptidase
Synonyms
- CPP32
- CPP32B
- Yama
- apopain
GenBank acession
- BC016926
Locus

4q35.1
Discovery year

1996-07-22
Entrez gene record

836
Pubmed identfication
- 8780721
RefSeq identity
- NM_004346
Classification
- Caspases
- Small nucleolar RNA protein coding host genes
VEGA ID

OTTHUMG00000133681

Identity

HGNC:2379
Gene

CRTAP
Long gene name

cartilage associated protein
Synonyms
- CASP
- LEPREL3
- P3H5
Synonyms name
- leprecan-like 3
- prolyl 3-hydroxylase family member 5 (non-enzymatic)
GenBank acession
- AJ006470
Locus

3p22.3
Discovery year

1999-10-19
Entrez gene record

10491
Pubmed identfication
- 9217321
- 10429950
Classification
- Prolyl 3-hydroxylase family
VEGA ID

OTTHUMG00000130746
Locus Specific Databases
- Osteogenesis Imperfecta Variant Database
- LRG_4

Identity

HGNC:1509
Gene

CASP8
Long gene name

caspase 8
Synonyms gene name
- caspase 8, apoptosis-related cysteine protease
- caspase 8, apoptosis-related cysteine peptidase
Synonyms
- MCH5
- MACH
- FLICE
- Casp-8
GenBank acession
- U60520
Locus

2q33.1
Discovery year

1996-11-11
Entrez gene record

841
Pubmed identfication
- 8681376
- 8681377
RefSeq identity
- NM_001228
Classification
- Caspases
- Death effector domain containing
- Death inducing signaling complex
- Ripoptosome
VEGA ID

OTTHUMG00000132821
Locus Specific Databases
- CASP8base: Mutation registry for Caspase 8 deficiency
- LRG_34

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data