Recombinant Human RAC2 Protein (His tag) 100µg
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Catalog number
PKSH030903-100µg
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Price
Please ask
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Size
100µg
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Synonym
EN-7;Gx;HSPC022;p21-Rac2
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Activity
NA
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Sequence
Met 1-Cys 189
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Fusion tag
N-His
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Accession
P15153
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Expressed Host
E. coli
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Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity
＞94 % as determined by SDS-PAGE
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Endotoxin
Please contact us for more information.
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Stability and Storage
Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass
22.6 kDa
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AP Mol Mass
25 kDa
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Formulation
Lyophilized from sterile PBS, 20% glycerol, pH 7.5
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Reconstitution
Please refer to it for detailed information.
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Background
Ras-related C3 botulinum toxin substrate 2 (Rac2) is a small G-protein belonging to the Ras subfamily of the GTPase family. Rac2 acts as an "on / off" switch for signal transduction cascades and motilities. When GDP is attached to the small G-protein, the enzyme is inactivated. Release of the GDP and replace of the GTP cativate the GTPasee. Rac2 remains active until the GTP is hydrolyzed to GDP. Rac2 is a hematopoietic-specific Rho family GTPase implicated as an important constituent of the NADPH oxidase complex and shares 92% amino acid identity with the ubiquitously expressed Rac1. The small G-protein Rac2 regulates the rearrangements of actin and membrane necessary for Fcy receptor-mediated phagocytosis by macrophages. Activated Rac2 binds to the p21-binding domain of PAK1 and this binding provided a basis for microscopic methods to localize activation of these G proteins inside cells.
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Conjugation
histidine
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
RAC2
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Short name
Recombinant RAC2 Protein (His tag) 100µg
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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Label
His
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Species
Human, Humans
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Alternative name
Rec. H. sapiens ras-related complement component 3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) Protein (histidine detection labelled) 100µg
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Alternative technique
rec
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Alternative to gene target
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2), EN-7 and Gx and HSPC022 and p21-Rac2, RAC2 and IDBG-6499 and ENSG00000128340 and 5880, GTP binding, nuclei, Rac2 and IDBG-159514 and ENSMUSG00000033220 and 19354, RAC2 and IDBG-638195 and ENSBTAG00000011043 and 327671
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Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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