Recombinant Human Nuclear-interacting partner of ALK (ZC3HC1)

Products_type

Recombinant Protein
Products_short_name

[Nuclear-interacting partner of ALK (ZC3HC1)]
Other_names

[nuclear-interacting partner of ALK isoform 2; Nuclear-interacting partner of ALK; nuclear-interacting partner of ALK; zinc finger C3HC-type containing 1; Nuclear-interacting partner of anaplastic lymphoma kinase; hNIPA; Zinc finger C3HC-type protein 1]
Products_gene_name

[ZC3HC1]
Products_gene_name_syn

[ZC3HC1]
Other_gene_names

[ZC3HC1; ZC3HC1; NIPA; HSPC216; NIPA; hNIPA]
Purity

>85% (SDS-PAGE)
Form

Lyophilized or liquid (Format to be determined during the manufacturing process)
Storage_stability

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

interacting partner ALK ZC3HC1
Gene symbol

ZC3HC1, ALK, ENPP7, TGFBR1, BMPR2
Short name

Recombinant -interacting partner of ALK (ZC3HC1)
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Host

E Coli or Yeast or Baculovirus or Mammalian Cell
Species

Human, Humans
Alternative name

Rec. H. sapiens Nuclear-interacting partner on anaplastic lymphoma receptor tyrosine kinase (zinc finger, C3HC-classification containing 1)
Alternative technique

rec
Alternative to gene target

zinc finger, C3HC-type containing 1, ZC3HC1 and IDBG-40971 and ENSG00000091732 and 51530, protein kinase binding, nuclei, Zc3hc1 and IDBG-132777 and ENSMUSG00000039130 and 232679, ZC3HC1 and IDBG-635405 and ENSBTAG00000011247 and 533550

Identity

HGNC:427
Gene

ALK
Long gene name

ALK receptor tyrosine kinase
Synonyms gene name
- anaplastic lymphoma kinase (Ki-1)
- anaplastic lymphoma receptor tyrosine kinase
Synonyms
- CD246
- ALK1
GenBank acession
- D45915
Locus

2p23.2-p23.1
Discovery year

1993-08-24
Entrez gene record

238
Pubmed identfication
- 8122112
RefSeq identity
- NM_004304
Classification
- Receptor tyrosine kinases
- CD molecules
VEGA ID

OTTHUMG00000152034
Locus Specific Databases
- LRG_488

Identity

HGNC:11772
Gene

TGFBR1
Long gene name

transforming growth factor beta receptor 1
Synonyms gene
- MSSE
- ESS1
Synonyms gene name
- multiple self-healing squamous epithelioma
- transforming growth factor beta receptor I
Synonyms
- ALK-5
- ACVRLK4
- ALK5
- TBRI
- TBR-i
Synonyms name
- activin A receptor type II-like kinase, 53kDa
Locus

9q22.33
Discovery year

1993-09-30
Entrez gene record

7046
Pubmed identfication
- 1319842
- 8530052
- 21358634
Classification
- Type 1 receptor serine/threonine kinases
VEGA ID

OTTHUMG00000020353
Locus Specific Databases
- LOVD - Center for Medical Genetics, Ghent, Belgium

Identity

HGNC:1078
Gene

BMPR2
Long gene name

bone morphogenetic protein receptor type 2
Synonyms gene
- PPH1
Synonyms gene name
- primary pulmonary hypertension 1
- bone morphogenetic protein receptor, type II (serine/threonine kinase)
- bone morphogenetic protein receptor type II
Synonyms
- BRK-3
- T-ALK
- BMPR3
- BMPR-II
GenBank acession
- Z48923
Locus

2q33.1-q33.2
Discovery year

1997-03-19
Entrez gene record

659
Pubmed identfication
- 7791754
RefSeq identity
- NM_001204
Classification
- Type 2 receptor serine/threonine kinases
VEGA ID

OTTHUMG00000133617
Locus Specific Databases
- LRG_712

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data