Recombinant Human ANP32A / PHAP1 Protein (His & GST tag)

  • Catalog number
    PKSH030963-20µg
  • Price
    Please ask
  • Size
    20µg
  • Synonym
    C15orf1;HPPCn;I1PP2A;LANP;MAPM;PHAP1;PHAPI;PP32
  • Activity
    NA
  • Sequence
    Glu 2-Lys 238
  • Fusion tag
    N-His & GST
  • Accession
    NP_006296.1
  • Expressed Host
    E. coli
  • Shipping
    In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
  • Purity
    >85 % as determined by SDS-PAGE
  • Endotoxin
    Please contact us for more information.
  • Stability and Storage
    Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Mol Mass
    55.4 kDa
  • AP Mol Mass
    50 kDa
  • Formulation
    Lyophilized from sterile 20mM Tris, 10% glycerol, 1mM DTT, 0.5mM GSH
  • Background
    acidic leucine-rich nuclear phosphoprotein 32 family member A, also known as acidic nuclear phosphoprotein pp32, Leucine-rich acidic nuclear protein, Mapmodulin, Potent heat-stable protein phosphatase 2A inhibitor I1PP2A, Putative HLA-DR-associated protein I, PHAPI and ANP32A, is a nucleus, cytoplasm and endoplasmic reticulum. ANP32A / LANP is expressed in all tissues tested. It is highly expressed in kidney and skeletal muscle, moderate levels of expression is in brain, placenta and pancreas. ANP32A / LANP is weakly expressed in lung. It is found in all regions of the brain examined (amygdala, caudate nucleus, corpus callosum, hippocampus and thalamus), with highest levels in amygdala. ANP32A / LANP is a component of the SET complex, which also contains SET, APEX1, HMGB2 and NME1. It directly interacts with SET. ANP32A / LANP also interacts with ATXN1/SCA1. ANP32A / LANP is implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. ANP32A / LANP plays a role in E4F1-mediated transcriptional repression.
  • Conjugation
    histidine
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    ANP32A   PHAP1   Protein   His   GST   tag  
  • Gene symbol
    MGST3, ANP32A-IT1, ANP32A
  • Short name
    Recombinant ANP32A / PHAP1 Protein (His & GST tag)
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
  • Label
    His
  • Species
    Human, Humans
  • Alternative name
    Rec. H. sapiens ANP32A / PHAP1 Protein (histidine & GST detection labelled)
  • Alternative technique
    rec
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    ANP32A intronic transcript 1
  • Synonyms gene
  • Synonyms gene name
    • chromosome 15 open reading frame 28
    • non-protein coding RNA 321
    • ANP32A intronic transcript 1 (non-protein coding)
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2004-06-29
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Intronic transcripts
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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