Recombinant Human ANP32A / PHAP1 Protein (His & GST tag)
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Catalog numberPKSH030963-20µg
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PricePlease ask
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Size20µg
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SynonymC15orf1;HPPCn;I1PP2A;LANP;MAPM;PHAP1;PHAPI;PP32
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ActivityNA
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SequenceGlu 2-Lys 238
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Fusion tagN-His & GST
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AccessionNP_006296.1
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Expressed HostE. coli
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ShippingIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity>85 % as determined by SDS-PAGE
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EndotoxinPlease contact us for more information.
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Stability and StorageSamples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass55.4 kDa
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AP Mol Mass50 kDa
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FormulationLyophilized from sterile 20mM Tris, 10% glycerol, 1mM DTT, 0.5mM GSH
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Backgroundacidic leucine-rich nuclear phosphoprotein 32 family member A, also known as acidic nuclear phosphoprotein pp32, Leucine-rich acidic nuclear protein, Mapmodulin, Potent heat-stable protein phosphatase 2A inhibitor I1PP2A, Putative HLA-DR-associated protein I, PHAPI and ANP32A, is a nucleus, cytoplasm and endoplasmic reticulum. ANP32A / LANP is expressed in all tissues tested. It is highly expressed in kidney and skeletal muscle, moderate levels of expression is in brain, placenta and pancreas. ANP32A / LANP is weakly expressed in lung. It is found in all regions of the brain examined (amygdala, caudate nucleus, corpus callosum, hippocampus and thalamus), with highest levels in amygdala. ANP32A / LANP is a component of the SET complex, which also contains SET, APEX1, HMGB2 and NME1. It directly interacts with SET. ANP32A / LANP also interacts with ATXN1/SCA1. ANP32A / LANP is implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. ANP32A / LANP plays a role in E4F1-mediated transcriptional repression.
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Conjugationhistidine
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolMGST3, ANP32A-IT1, ANP32A
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Short nameRecombinant ANP32A / PHAP1 Protein (His & GST tag)
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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LabelHis
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SpeciesHuman, Humans
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Alternative nameRec. H. sapiens ANP32A / PHAP1 Protein (histidine & GST detection labelled)
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Alternative techniquerec
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Gene info
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Identity
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Gene
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Long gene namemicrosomal glutathione S-transferase 3
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-10-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Microsomal glutathione S-transferases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameANP32A intronic transcript 1
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Synonyms gene
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Synonyms gene name
- chromosome 15 open reading frame 28
- non-protein coding RNA 321
- ANP32A intronic transcript 1 (non-protein coding)
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-06-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Intronic transcripts
Gene info
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Identity
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Gene
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Long gene nameacidic nuclear phosphoprotein 32 family member A
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Synonyms gene
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Synonyms gene name
- acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-02-13
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Entrez gene record
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Pubmed identfication
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Classification
- INHAT complex
- SET complex
- MicroRNA protein coding host genes
- ANP32 acidic nuclear phosphoproteins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data