Recombinant Feline CD40 Ligand (CD40LG)

• Catalog number
  RP0988F-005
• Price
  Please ask
• Size
  5 ug

• Product Type
  Protein
• Target
  CD40 Ligand
• Alias
  TNFSF5
• MW
  15.9 kDa
• Form
  Lyophilized
• Storage
  -20 °C
• Shipping
  Ambient
• Entrez Gene ID
  493850
• Protein Sequence
  MQKGDQDPRV AAHVISEASS STASVLQWAP KGYYTISSNL VTLENGKQLA VKRQGLYYIY AQVTFCSNRE ASSQAPFIAS LCLHSPSGSE RVLLRAANAR SSSKPCGQQS IHLGGVFELH PGASVFVNVT DPSQVSHGTG FTSFGLLKL (149)
• Source
  Yeast
• Description
  FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CD40   Ligand   CD40LG  
• Gene symbol
  CD40, CD40LG
• Short name
  Recombinant Feline CD40 Ligand (CD40LG)
• Technique
  Recombinant, Feline, felines, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. kingfisherbiotech advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Feline, Sometimes til 5% of an area felines have specific IgGs for the feline retroviral feLV infecting Felidae. Also distemper and leukemia virusses apear in cats and have their specific IgG antibodies that are very stable. All cats used for producing immunoglobulins are screened and tested virus negative. Cat seras have usually higher IgG tirters than dog serum. Feline range = 10 to 20 mg/ml IgGs.
• Alternative name
  Rec. Feline CD40 molecule, tumor necrosis factor receptor superfamily member 5 Ligand (CD40 molecule, tumor necrosis factor receptor superfamily member 5 ligand)
• Alternative technique
  rec, cats
• Alternative to gene target
  CD40 molecule, TNF receptor superfamily member 5, Bp50 and CDW40 and p50 and TNFRSF5, CD40 and IDBG-78904 and ENSG00000101017 and 958, ubiquitin protein ligase binding, Extracellular, Cd40 and IDBG-212533 and ENSMUSG00000017652 and 21939, BT.42498 and IDBG-643036 and ENSBTAG00000020736 and 286849

Gene info

• Identity
  HGNC:11919
• Gene
  CD40
• Long gene name
  CD40 molecule
• Synonyms gene
  • TNFRSF5
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 5
  • CD40 molecule, TNF receptor superfamily member 5
• Synonyms
  • p50
  • Bp50
• GenBank acession
  • X60592
• Locus
  20q13.12
• Discovery year
  1993-08-27
• Entrez gene record
  958
• Pubmed identfication
  • 7687385
  • 2998589
• RefSeq identity
  • NM_001250
• Classification
  • CD molecules
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000033053
• Locus Specific Databases
  • CD40base: Mutation registry for CD40 deficiency (previously known as TNFRSF5base)
  • LRG_40

Gene info

• Identity
  HGNC:11935
• Gene
  CD40LG
• Long gene name
  CD40 ligand
• Synonyms gene
  • HIGM1
  • IMD3
  • TNFSF5
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 5 (hyper-IgM syndrome)
• Synonyms
  • CD40L
  • TRAP
  • gp39
  • hCD40L
  • CD154
• Synonyms name
  • CD40 antigen ligand
  • tumor necrosis factor (ligand) superfamily member 5
  • T-B cell-activating molecule
  • TNF-related activation protein
  • hyper-IgM syndrome
• GenBank acession
  • X67878
• Locus
  Xq26.3
• Discovery year
  1989-06-30
• Entrez gene record
  959
• Pubmed identfication
  • 1427881
  • 7678782
• RefSeq identity
  • NM_000074
• Classification
  • CD molecules
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000022512
• Locus Specific Databases
  • CD40Lbase: Mutation registry for X-linked Hyper-IgM syndrome
  • Global Variome shared LOVD
  • LRG_141

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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