RCAN2 Isoform 2 Recombinant Protein

RCAN2 Isoform 2 Recombinant Protein is available 1 time from Proscience labs

  • Keep at
    Store in working aliquots at -70˚C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
  • NCBI ID
    53901
  • Protein is used in
    E, WB, MS
  • Activity
    not available
  • Source
    Mus musculus
  • Protein's origin
    Mouse
  • Uniprot
    Q9JHG2
  • Recombinant in
    E. coli
  • Vial
    Liquid
  • SEQUENCE
    aa 2 - 197
  • Gene name
    regulator of calcineurin 2
  • Pureity
    ~95%
  • Accession nr
    AAH62141
  • About recombinant protein
    Regulator of calcineurin 2 (RCAN2), also known as ZAKI4 and DSCR1L1, is expressed as two isoforms differing at their N-terminus. The longer of the two (isoform 1) is expressed exclusively in the brain, while isoform 2 is ubiquitously expressed, with highest expression in brain, heart, and muscle (1,2). Both isoforms bind to the catalytic subunit of calcineurin, a Ca++-dependent protein phosphatase involved in several neuronal functions, though their C-terminal region and inhibit calcineurin’s activity (3). Unlike isoform 1 of RCAN2, the expression of the second isoform is not induced by the thyroid hormone T3 (3). RCAN2 is a member of a family of three endogenous calcineurin regulators that are located near the minimal supernumerary fragment of chromosome 21 in individuals with Down syndrome, suggesting that they play a role in this syndrome (4).
  • His tag on the recombinant protein
    Fusion Partner: C-terminal His-tag
  • KDa of reombinant
    26 kDa (Calculated)
  • Use of recmbinant
    This recombinant protein can be used for WB, ELISA, MS and neutralization assays.
  • Suspention medium
    100mM sodium phosphate, 10mM Tris, 500mM NaCl, 25 mM imidazole, 2mM MgCl2, 10% gycerol
  • Rec. PROTEIN GI#
    38328420
  • About
    Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
  • Other name of the recombinant
    RCAN2 Antibody: Csp2, MCIP2, ZAKI-4, Dscr1l1, Zaki4, Calcipressin-2, Calcineurin inhibitory protein ZAKI-4
  • Gene target
  • Gene symbol
    Rcan2
  • Short name
    RCAN2 Isoform 2 Recombinant Protein
  • Technique
    Recombinant
  • Alternative name
    RCAN2 Isoform 2 recombinant Protein
  • Alternative technique
    rec

95-114 | RCAN2 Isoform 2 Recombinant Proteinsize: 0.05 mg | 399.72 USD

  • Catalog number
    95-114
  • Supplier
  • Price
    399.72 USD
  • Size
    0.05 mg
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
0. Gene info
MeSH Data
  • Name
  • Concept
    Scope note:The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
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