RBBP6 Polyclonal Antibody

• Catalog number
  CAC07924
• Price
  Please ask
• Size
  50 μg

• Other name
  E3 ubiquitin-protein ligase RBBP6,Proliferation potential-related protein,Protein P2P-R,Retinoblastoma-binding Q protein 1,RBQ-1,Retinoblastoma-binding protein 6,p53-associated cellular protein of testis,RBBP6,P2PR,PACT,RBQ1,My038
• Immunogen
  Recombinant Human E3 ubiquitin-protein ligase RBBP6 protein (351-97AA)
• Verified reactivity
  Human, Mouse
• Verified applications
  ELISA,WB,IHC,IF. Recommended dilution:WB:1:500-1:5000,IHC:1:20-1:200,IF:1:50-1:200
• Raised in
  Rabbit
• Clonality
  Polyclonal
• Protein number
  Q7Z6E9
• Gene number
  Please refer to GenBank
• NCBI number
  Please refer to NCBI
• Purity
  Protein G purified, >95%
• Storage recommendation
  Aliquot and store at -20°C. Minimize freezing and thawing.
• Use before
  1 year
• Shipping requirements
  Blue ice
• Estimated production time
  3-7 business days
• Supplementary information
  E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome (PubMed:18851979). May play a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in increase of MDM2-mediated ubiquitination and degradation of p53/TP53; may function as negative regulator of p53/TP53, leading to both apoptosis and cell growth (By similarity). Regulates DNA-replication and the stability of chromosomal common fragile sites (CFSs) in a ZBTB38- and MCM10-dependent manner. Controls ZBTB38 protein stability and abundance via ubiquitination and proteasomal degradation, and ZBTB38 in turn negatively regulates the expression of MCM10 which plays an important role in DNA-replication (PubMed:24726359).
• Notes
  For research use only. Not for diagnostic procedures.
• Hyperlink
• Properties
  If you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  RBBP6  
• Gene symbol
  RBBP6
• Short name
  RBBP6 Polyclonal Antibody
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Label
  Unconjugated
• Alternative name
  RBBP6 polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:9889
• Gene
  RBBP6
• Long gene name
  RB binding protein 6, ubiquitin ligase
• Synonyms gene name
  • retinoblastoma-binding protein 6
  • retinoblastoma binding protein 6
• Synonyms
  • P2P-R
  • PACT
  • SNAMA
• Synonyms name
  • proliferation potential-related protein
• Locus
  16p12.1
• Discovery year
  1995-08-17
• Entrez gene record
  5930
• Pubmed identfication
  • 8595913
  • 16396680
  • 18851979
• RefSeq identity
  • NM_006910
• Classification
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000096991

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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