RB1CC1 Antibody

• Catalog number
  bs-8165R
• Price
  Please ask
• Size
  0.1ml

• Long name
  RB1CC1 Primary Polyclonal Antibody
• Also known as
  RB1CC1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  RB1CC1
• Specificity
  This is a highly specific antibody against RB1CC1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  515-550/1594
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RB1CC1
• Gene ID number
  9821
• Swiss Prot
  Q8TDY2
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111. Involved in autophagy. Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) duting S.typhimurium infection and subsequent xenophagy. Autophagy positively regulates repair of DNA damage induced by ionizing radiation and negatively regulates apoptosis. Plays an indispensible role in fetal hematopoiesis and in the regulation of neuronal homeostasis (By similarity). Implicated in the regulation of RB1 expression. Functions as a DNA-binding transcription factor. Is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. Expression is, thus, a prerequisite for myogenic differentiation. Inhibits PTK2/FAK1 and PTK2B/PYK2 activity and activation of downstream signaling pathways.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  CC1; ATG17; FIP200; PPP1R131; RB1-inducible coiled-coil protein 1; FAK family kinase-interacting protein of 200 kDa; RB1CC1; KIAA0203; RBICC
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  RB1CC1  
• Gene symbol
  RB1CC1
• Short name
  Anti-RB1CC1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  RB1CC1 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  RB1-inducible coiled-coil 1, ATG17 and CC1 and FIP200 and PPP1R131, RB1CC1 and IDBG-21487 and ENSG00000023287 and 9821, protein kinase binding, nuclei, Rb1cc1 and IDBG-131892 and ENSMUSG00000025907 and 12421, BT.55953 and IDBG-644388 and ENSBTAG00000000878 and 539858

Gene info

• Identity
  HGNC:15574
• Gene
  RB1CC1
• Long gene name
  RB1 inducible coiled-coil 1
• Synonyms
  • KIAA0203
  • Cc1
  • DRAGOU14
  • FIP200
  • ATG17
  • PPP1R131
• Synonyms name
  • 200 kDa FAK family kinase-interacting protein
  • phosphatase 1, regulatory subunit 131
• GenBank acession
  • AB059622
• Locus
  8q11.23
• Discovery year
  2001-06-01
• Entrez gene record
  9821
• Pubmed identfication
  • 11850849
  • 7724523
  • 18443221
• RefSeq identity
  • NM_014781
• Classification
  • Autophagy related
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000164268

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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