Recombinant Rat OLR1 / LOX1 Protein (His tag) 50µg

  • Catalog number
    PKSR030274-50µg
  • Price
    Please ask
  • Size
    50µg
  • Synonym
    OLR1;Lox1;Oldlr1
  • Activity
    NA
  • Sequence
    Leu60-Gln364
  • Fusion tag
    N-His
  • Accession
    O70156
  • ExpressedHost
    HEK293 Cells
  • Shipping
    In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
  • Purity
    > 90 % as determined by SDS-PAGE
  • Endotoxin
    < 1.0 EU per μg of the protein as determined by the LAL method
  • Stability and Storage
    Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Mol Mass
    37.9 kDa
  • AP Mol Mass
    43-47 KDa
  • Formulation
    Lyophilized from sterile PBS, pH 7.4
  • Background
    Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1 or OLR1), also known as lectin-type oxidized LDL receptor 1 (LOX1), is a receptor protein that belongs to the C-type lectin superfamily. LOX1 is a multi-ligand receptor originally identified as the endothelial oxidized LDL receptor. OLR1 / LOX1 was isolated from an aortic endothelial cell, and recently it has been discovered in macrophages and vascular smooth muscle cells in artery vessels. The expression of LOX1 is inducted by inflammatory stimuli and oxidative stimuli. This protein binds, internalizes and degrades oxidized low-density lipoprotein. LOX1 may play an important role in the progression of vulnerable carotid plaque and might regulate vulnerable plaque formation in cooperation with MMPs and TIMP-2. In clinical, LOX1 is thought to be involved in the development of atherosclerotic lesions. 
  • Conjugation
    histidine
  • About
    Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
  • Latin name
    Rattus norvegicus
  • Source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    OLR1   LOX1   Protein   His   tag   50µg  
  • Gene symbol
    OLR1
  • Short name
    Recombinant OLR1 / LOX1 Protein (His tag) 50µg
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
  • Host
    Rat
  • Label
    His
  • Species
    Rat, Rats
  • Alternative name
    Rec. Rat oxidized low density lipoprotein (lectin-like) receptor 1 / LOX1 Protein (histidine detection labelled) 50µg
  • Alternative technique
    rec
  • Alternative to gene target
    oxidized low density lipoprotein (lectin-like) receptor 1, CLEC8A and LOX1 and LOXIN and SCARE1 and SLOX1, OLR1 and IDBG-18612 and ENSG00000173391 and 4973, carbohydrate binding, nuclei, Olr1 and IDBG-192019 and ENSMUSG00000030162 and 108078, OLR1 and IDBG-639562 and ENSBTAG00000004547 and 281368
Gene info
  • Identity
  • Gene
  • Long gene name
    oxidized low density lipoprotein receptor 1
  • Synonyms gene name
    • oxidised low density lipoprotein (lectin-like) receptor 1
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1998-01-16
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • C-type lectin domain containing
    • Scavenger receptors
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.
  • Tree numbers
    • E05.393.220
  • Qualifiers
    drug effects, methods, radiation effects
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