Rat TRAIL-R3(Tumor Necrosis Factor Related Apoptosis Inducing Ligand Receptor 3) EIA Kit

  • Catalog number
    E-EL-R1039-96T
  • Price
    Please ask
  • Size
    96Test
  • Detection Type
    Colormetric
  • Target Species
    Rat
  • Target Synonym
    NA
  • Test principle
    This EIA kit uses the Sandwich-EIA principle. The micro EIA plate provided in this kit has been pre-coated with an antibody specific to Rat TRAIL-R3. Standards or samples are added to the micro EIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Rat TRAIL-R3 and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Rat TRAIL-R3, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm ± 2 nm. The OD value is proportional to the concentration of Rat TRAIL-R3. You can calculate the concentration of Rat TRAIL-R3 in the samples by comparing the OD of the samples to the standard curve.
  • Sensitivity
    0.1ng/mL
  • Detection Range
    0.16~10ng/mL
  • Target Name
    TRAIL-R3
  • UNIProt ID
    NA
  • Tested Sample Types
    Serum, Plasma, Cell supernatant
  • Product Name
    Rat TRAIL-R3(Tumor Necrosis Factor Related Apoptosis Inducing Ligand Receptor 3) EIA Kit
  • Type
    Sandwich
  • Description
    This 1 is suited for programmed cell-death studies. This ELISA test kit or EIA Enzyme immuno assay is an enzyme linked immuno assay supplied as coated 96 well plates with antigen or antibody and needs to be stored at +4°C. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Properties
    MeSH E05 478 566 350 170 Enzyme-Linked Immunosorbent Assay
  • About
    Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
  • Latin name
    Rattus norvegicus
  • Gene target
  • Gene symbol
    TNFSF10, TNFRSF10C, TNFRSF10B
  • Short name
    TRAIL-R3(Tumor Necrosis Factor Apoptosis Ligand Receptor 3) EIA Kit
  • Technique
    apoptosis, EIA, apoptosis pathway, eia
  • Host
    Rat
  • Species
    Rat, Rats
  • Alternative name
    Rat TRAIL-R3(Tumor Necrosis Factor Related programmed cellular destruction Inducing Ligand Receptor 3) EIA reagent
  • Alternative technique
    celldeath, kits, elisas
  • Alternative to gene target
    v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
  • Tissue
    tumor
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    TNF receptor superfamily member 10c
  • Synonyms gene name
    • tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1998-12-04
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • CD molecules
    • Tumor necrosis factor receptor superfamily
  • VEGA ID
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
  • Tree numbers
    • E01.370.225.500.383.910
    • E01.370.225.500.388.930
    • E05.200.500.383.910
    • E05.200.500.388.930
    • E05.242.383.910
    • E05.242.417.500
    • E05.337.550.200.800
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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