Monoclonal mouse anti-rat MHC class II (RT-1B) antigen

• Catalog number
  GEN660245
• Price
  Please ask
• Size
  1000ug

• Also known as
  MHC Class II
• Other names
  MHC class II beta chain, partial; MHC class II beta chain; N/A; N/A; MHC class II beta chain
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  RT-1B
• Gene name synonims
  N/A
• Other gene names
  N/A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1, kappa for MAb 3D6
• Clone
  3D6
• Host organism
  N/A
• Species reactivity
  N/A; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  MHC class II RT-1B antigen. MAb reacts with monomorphic determinant on beta chain of RT-1B molecules. MAb 3D6 does not cross-react with RT-1A,-C,-D rat MHC products.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Chromatography on protein A Sepharose
• Form Appearance
  PBS, pH 7.4, 0.1 % sodium azide (NaN3)
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius.
• Tested applications
  N/A
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Antigens are peptides or recombinant or native dependent on the production method.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus, Rattus norvegicus

• Gene target
  Monoclonal   MHC   class   RT-1B  
• Gene symbol
  IGHD1OR15-1B, XCL2, APH1B, HOMER1, IL1B, TCF4, MARK2, PEDS1-UBE2V1, PPP1CB, RBM8A
• Short name
  Monoclonal mouse anti- MHC class II (RT-1B) antigen
• Technique
  antigen, anti-, Mouse, anti, antibody to, antibodies, antigenes, Monoclonals or monoclonal antibodies, mouses
• Host
  mouse
• Species
  Rat, Mouses, Rats
• Alternative name
  Anti-Monoclonal mouse anti-rat MHC class II (RT-1B) antigen
• Alternative technique
  antigenes, murine, antibodies

Gene info

• Identity
  HGNC:5488
• Gene
  IGHD1OR15-1B
• Long gene name
  immunoglobulin heavy diversity 1/OR15-1B (non-functional)
• Synonyms gene name
  • immunoglobulin heavy diversity 1/OR15-1B
• Synonyms
  • IGHD1/OR15-1B
  • IGHD1OR151B
• GenBank acession
  • X55576
• Locus
  15q11.2
• Discovery year
  2000-04-17
• Entrez gene record
  28334
• Pubmed identfication
  • 2114977
• Classification
  • Immunoglobulin heavy (IGH) orphons
• VEGA ID
  OTTHUMG00000184585

Gene info

• Identity
  HGNC:10646
• Gene
  XCL2
• Long gene name
  X-C motif chemokine ligand 2
• Synonyms gene
  • SCYC2
• Synonyms gene name
  • small inducible cytokine subfamily C, member 2
  • chemokine (C motif) ligand 2
• Synonyms
  • SCM-1b
• GenBank acession
  • BC070309
• Locus
  1q24.2
• Discovery year
  1997-02-19
• Entrez gene record
  6846
• Pubmed identfication
  • 7875320
• RefSeq identity
  • NM_003175
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000034549

Gene info

• Identity
  HGNC:24080
• Gene
  APH1B
• Long gene name
  aph-1 homolog B, gamma-secretase subunit
• Synonyms gene name
  • anterior pharynx defective 1 homolog B (C. elegans)
  • APH1B gamma secretase subunit
• Synonyms
  • PSFL
  • APH-1B
  • DKFZp564D0372
• GenBank acession
  • AY358698
• Locus
  15q22.2
• Discovery year
  2005-02-08
• Entrez gene record
  83464
• Pubmed identfication
  • 12110170
  • 11230166
• RefSeq identity
  • NM_031301
• VEGA ID
  OTTHUMG00000132863

Gene info

• Identity
  HGNC:17512
• Gene
  HOMER1
• Long gene name
  homer scaffold protein 1
• Synonyms gene name
  • homer homolog 1 (Drosophila)
  • homer scaffolding protein 1
• Synonyms
  • Ves-1
  • SYN47
  • HOMER-1B
• GenBank acession
  • BC015502
• Locus
  5q14.1
• Discovery year
  2003-01-28
• Entrez gene record
  9456
• Pubmed identfication
  • 9808459
  • 9808458
• RefSeq identity
  • NM_004272
• Classification
  • Homer scaffold proteins
• VEGA ID
  OTTHUMG00000134278

Gene info

• Identity
  HGNC:5992
• Gene
  IL1B
• Long gene name
  interleukin 1 beta
• Synonyms
  • IL1F2
  • IL-1B
  • IL1-BETA
• GenBank acession
  • M15330
• Locus
  2q14.1
• Discovery year
  1989-03-31
• Entrez gene record
  3553
• Pubmed identfication
  • 2954882
  • 2989698
• RefSeq identity
  • NM_000576
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131344

Gene info

• Identity
  HGNC:11634
• Gene
  TCF4
• Long gene name
  transcription factor 4
• Synonyms
  • SEF2-1B
  • ITF2
  • bHLHb19
  • E2-2
• Synonyms name
  • SL3-3 enhancer factor 2
  • class B basic helix-loop-helix protein 19
  • immunoglobulin transcription factor 2
• GenBank acession
  • M74719
• Locus
  18q21.2
• Discovery year
  1990-10-16
• Entrez gene record
  6925
• Pubmed identfication
  • 9302263
  • 2308860
• RefSeq identity
  • NM_003199
• Classification
  • Basic helix-loop-helix proteins
• VEGA ID
  OTTHUMG00000132713
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:3332
• Gene
  MARK2
• Long gene name
  microtubule affinity regulating kinase 2
• Synonyms gene
  • EMK1
• Synonyms gene name
  • ELKL motif kinase
  • MAP/microtubule affinity-regulating kinase 2
• Synonyms
  • PAR-1
  • Par1b
  • PAR-1B
• Synonyms name
  • ELKL motif kinase 1
  • serine/threonine kinase
  • protein-serine/threonine kinase
  • Ser/Thr protein kinase PAR-1B
• GenBank acession
  • BC008771
• Locus
  11q13.1
• Discovery year
  1994-12-08
• Entrez gene record
  2011
• Pubmed identfication
  • 9730619
  • 10516437
• RefSeq identity
  • NM_017490
• VEGA ID
  OTTHUMG00000160504

Gene info

• Identity
  HGNC:33521
• Gene
  PEDS1-UBE2V1
• Long gene name
  PEDS1-UBE2V1 readthrough
• Synonyms gene
  • TMEM189-UBE2V1
• Synonyms gene name
  • TMEM189-UBE2V1 readthrough
• Synonyms
  • Kua-UEV
  • CROC-1B
• GenBank acession
  • U39361
• Locus
  20q13.13
• Discovery year
  2007-07-31
• Entrez gene record
  387522
• Pubmed identfication
  • 11076860
• VEGA ID
  OTTHUMG00000033085

Gene info

• Identity
  HGNC:9282
• Gene
  PPP1CB
• Long gene name
  protein phosphatase 1 catalytic subunit beta
• Synonyms gene name
  • protein phosphatase 1, catalytic subunit, beta isoform
  • protein phosphatase 1, catalytic subunit, beta isozyme
• Synonyms
  • PP1B
  • PP-1B
  • PP1beta
  • PP1c
  • MP
  • PPP1beta
• Synonyms name
  • myosin phosphatase
• Locus
  2p23.2
• Discovery year
  1993-01-22
• Entrez gene record
  5500
• Pubmed identfication
  • 8312365
• Classification
  • Protein phosphatase catalytic subunits
• VEGA ID
  OTTHUMG00000152011

Gene info

• Identity
  HGNC:9905
• Gene
  RBM8A
• Long gene name
  RNA binding motif protein 8A
• Synonyms gene
  • RBM8
• Synonyms
  • ZNRP
  • BOV-1A
  • BOV-1B
  • BOV-1C
  • RBM8B
  • Y14
• Synonyms name
  • binder of OVCA1
• GenBank acession
  • AF127761
• Locus
  1q21.1
• Discovery year
  1999-05-05
• Entrez gene record
  9939
• Pubmed identfication
  • 11004516
  • 11013075
• RefSeq identity
  • NM_005105
• Classification
  • Spliceosomal P complex
  • RNA binding motif containing
  • Exon junction complex
• VEGA ID
  OTTHUMG00000013736
• Locus Specific Databases
  • LRG_574

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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