RASSF1 Antibody, ALEXA FLUOR 647

• Catalog number
  bs-1234R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  RASSF1 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-RASSF1 PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  RASSF1
• Specificity
  This is a highly specific antibody against RASSF1.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  150-195/340
• Subcellular location
  Cytoplasm, Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RASSF1
• Gene ID Number
  11186
• Swiss Prot
  Q9NS23
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Potential tumor suppressor. Required for death receptor-dependent apoptosis. Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF1 stimulation. Isoform A interacts with CDC2, an activator of the anaphase-promoting complex, APC, resulting in the inhibition of APC activity and mitotic progression. Inhibits proliferation by negatively regulating cell cycle progression at the level of G1/S-phase transition by regulating accumulation of cyclin D1 protein. Isoform C has been shown not to perform these roles, no function has been identified for this isoform. Isoform A disrupts interactions among MDM2, DAXX and USP7, thus contributing to the efficient activation of TP53 by promoting MDM2 self-ubiquitination in cell-cycle checkpoint control in response to DNA damage.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  123F2; RDA32; NORE2A; RASSF1A; REH3P21; Ras association domain-containing protein 1; RASSF1
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-RASSF1 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  RASSF1  
• Gene symbol
  RASSF1-AS1, RASSF1
• Short name
  Anti-RASSF1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  RASSF1 Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:49091
• Gene
  RASSF1-AS1
• Long gene name
  RASSF1 antisense RNA 1
• Synonyms
  • ANRASSF1
• GenBank acession
  • KC330992
• Locus
  3p21.3
• Discovery year
  2013-09-01
• Entrez gene record
  102060282
• Pubmed identfication
  • 23990798
• RefSeq identity
  • NR_109831
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000189572

Gene info

• Identity
  HGNC:9882
• Gene
  RASSF1
• Long gene name
  Ras association domain family member 1
• Synonyms gene name
  • Ras association (RalGDS/AF-6) domain family member 1
• Synonyms
  • NORE2A
  • REH3P21
  • RDA32
  • 123F2
• GenBank acession
  • AF132675
• Locus
  3p21.31
• Discovery year
  2000-05-30
• Entrez gene record
  11186
• Classification
  • Ras association domain family
• VEGA ID
  OTTHUMG00000149958

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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