rac-tert-Butyl 2-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate

• Catalog number
  T117575
• Price
  Please ask
• Size
  5 mg

• Chemical available in other sizes
  Please inquire size and price
• Stock availability
  Please Inquire
• Cas number
  1268524-69-1
• Chemical s molecular weight
  456.99
• Chemical s main applications
  rac-Tert-butyl 2-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate is the isomer of (S)-(+)-Tert-butyl 2-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate (T117580), which is BET bromodomain inhibitor, also activates HIV latency through antagonizing Brd4 inhibition of Tat-transactivation.
• Other name
  4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic Acid 1,1-Dimethylethyl Ester; rac-JQ1; Tert-butyl 2-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate;
• Chemical s formula
  C23H25ClN4O2S
• Physical properties
  No Data Available
• Melting temperature
  No Data Available
• Boiling temperature
  No Data Available
• Chemical s soluble in
  No Data Available
• Stability conditions
  No Data Available
• Storage
  No Data Available
• Chemical s specifications

• Gene target
  rac-tert-Butyl   4-Chlorophenyl   9-trimethyl-6H-thieno[3   2-f][1   4]triazolo[4   3-a][1   4]diazepin-6-yl   acetate  
• Gene symbol
  MIR1302-6, PIRC24, PIRC28, PIRC26, ADCP1, PIRC27, PIRC25
• Short name
  rac-tert-Butyl 2-(4-(4-Chlorophenyl)-2 3 9-trimethyl-6H-thieno[3 2-f][1 2 4]triazolo[4 3-a][1 4]diazepin-6-yl)acetate
• Alternative name
  rac-telomerase reverse transcriptase-Butyl 2-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate
• Alternative to gene target
  telomerase reverse transcriptase, CMM9 and DKCA2 and DKCB4 and EST2 and hEST2 and hTRT and PFBMFT1 and TCS1 and TP2 and TRT, TERT and IDBG-10998 and ENSG00000164362 and 7015, telomeric RNA binding, nuclei, Tert and IDBG-165912 and ENSMUSG00000021611 and 21752, BT.60929 and IDBG-632169 and ENSBTAG00000012567 and 518884

Gene info

• Identity
  HGNC:35298
• Gene
  MIR1302-6
• Long gene name
  microRNA 1302-6
• Synonyms gene
  • MIRN1302-6
• Synonyms
  • hsa-mir-1302-6
• Locus
  7p21.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302140
• RefSeq identity
  • NR_031635
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:37528
• Gene
  PIRC24
• Long gene name
  piwi-interacting RNA cluster 24
• Locus
  6
• Discovery year
  2009-11-05
• Entrez gene record
  100313810
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37532
• Gene
  PIRC28
• Long gene name
  piwi-interacting RNA cluster 28
• Locus
  6
• Discovery year
  2009-11-05
• Entrez gene record
  100313893
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37530
• Gene
  PIRC26
• Long gene name
  piwi-interacting RNA cluster 26
• Locus
  6
• Discovery year
  2009-11-05
• Entrez gene record
  100313852
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:229
• Gene
  ADCP1
• Long gene name
  adenosine deaminase complexing protein 1
• Locus
  6
• Discovery year
  1986-01-01
• Entrez gene record
  106
• Pubmed identfication
  • 279003
  • 6933468
  • 6974523

Gene info

• Identity
  HGNC:37531
• Gene
  PIRC27
• Long gene name
  piwi-interacting RNA cluster 27
• Locus
  6
• Discovery year
  2009-11-05
• Entrez gene record
  100313907
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37529
• Gene
  PIRC25
• Long gene name
  piwi-interacting RNA cluster 25
• Locus
  6
• Discovery year
  2009-11-05
• Entrez gene record
  100313851
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

MeSH Data

• Name
  Radioallergosorbent Test
• Concept
  Scope note: An in vitro allergen radioimmunoassay in which allergens are coupled to an immunosorbent. The coupled allergens bind the IgE in the sera of patients which in turn binds radioisotope-labeled anti-IMMUNOGLOBULIN E antibodies.
• Tree numbers
  • E01.370.225.812.735.830
  • E05.200.812.735.830
  • E05.478.566.380.810
  • E05.478.566.639.810
  • E05.478.594.760.830
  • E05.601.470.380.810
  • E05.601.470.639.810
• Qualifiers
  ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data

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