Rabbit Polyclonal (IgG) to Human CTSB / Cathepsin B
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Catalog number
MBS248485
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Price
Please ask
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Size
0.05 mL
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Products_type
Antibody
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Products_short_name
[CTSB / Cathepsin B]
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Products_name_syn
[Anti-CTSB / Cathepsin B Antibody (aa42-339) IHC-plus; CTSB; Cathepsin B1; Cathepsin B; Cathepsins B; CPSB; Cysteine protease; Preprocathepsin B; APP secretase; APPS; Human CTSB; Cathepsin B]
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Other_names
[cathepsin B preproprotein; Cathepsin B; cathepsin B; cathepsin B1; APP secretase; cysteine protease; amyloid precursor protein secretase; cathepsin B; APP secretase; APPS; Cathepsin B1Cleaved into the following 2 chains:Cathepsin B light chain; Cathepsin B heavy chain]
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Products_gene_name
[CTSB]
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Other_gene_names
[CTSB; CTSB; APPS; CPSB; CPSB; APPS]
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Clonality
Polyclonal
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Reactivity
Human
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Specificity
Human CTSB / Cathepsin B
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Purity
Immunoaffinity Purified
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Form
PBS, pH 7, 20% glycerol, 0.01% Thimerosal
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Concentration
1 mg/ml
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Storage_stability
Keep as concentrated solution. Aliquot and store at -20 degree C or below. Avoid multiple freeze-thaw cycles.
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Tested_application
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
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Gene
CTS protease activity also measured by zymograph electrophoresis of Cathepsins. This cathepsin is supplied in 1.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Immunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures. Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Group
Polyclonals and antibodies
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Latin name
Oryctolagus cuniculus
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Gene target
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Gene symbol
CTSB
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Short name
Rabbit Polyclonal (IgG) CTSB / Cathepsin B
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Technique
Polyclonal, Rabbit, IgG, IgGs, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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Host
Rabbit, Rabbits
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Isotype
IgG, IgG
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Species
Human, Humans
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Alternative name
production species: rabbit polyclonal (Immunoglobulin G) to H. sapiens cathepsin B / Cathepsin B
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Alternative technique
polyclonals, rabbit-anti, immunoglobulins
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Alternative to gene target
cathepsin B, APPS and CPSB, CTSB and IDBG-7654 and ENSG00000164733 and 1508, proteoglycan binding, nuclei, Ctsb and IDBG-172314 and ENSMUSG00000021939 and 13030, CTSB and IDBG-629395 and ENSBTAG00000012442 and 281105
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Gene info
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Identity
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Gene
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Long gene name
cathepsin B
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GenBank acession
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Locus
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Discovery year
2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Product images
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