Rabbit Polyclonal IgG Anti-Survivin (IAP)

• Catalog number
  SUR002-G
• Price
  Please ask
• Size
  5 ml

• Availability
  Please contact us to check the availability
• Immunogen
  Synthetic C-terminal peptide sequence of human Survivin
• Specificity
  Human Survivin
• Species reactivity
  Human, mouse, others not tested
• Product presentation
  Affinity purified IgG from rabbit serum in PBS, BSA, NaN3
• Product category
  Primary Antibody
• Antibody s raised in
  Rabbit
• Antibody s isotype
  IgG
• Antibody s clone
  polyclonal
• Product is supplied as
  ready to use
• Recommended concentration for use
  neat
• Protein concentration
  N/A
• Positive control
  Pancreas (alpha-cells), Prostate carcinoma
• Pretreatment
  After formaldehyde fixation antigen unmasking at 96-100°C is recommended (use citrate buffer Art. No. DE000 or Unmasking Fluid G on glycol basis Art. No. DE007 respectively).
• Tested applications
  IHC(P)
• Recommended secondary reagent
  We recommend the use of Gentaur's Universal Staining System DAB (Art. No. DA005) or AEC (Art. No. AE005), for higher sensitivities VECTASTAIN Elite ABC (Art. No. PK-6101) or ABC AP (Art. No. AK-5001) systems are applicable.
• Storage method
  Store at 2-8°C
• UniProt number
  O15392
• Litterature
  1. Ambrosini G, Adida C, Altieri DC. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med. 1997 Aug;3(8):917-21. 2. Liggins C et al. (2003) Pediatric Dev. Pathol. 6: 392-397. 3. Kuar P., et al. (2004) Arch. Pathol. Lab. Med. 128: 39-43.
• Tips
  *Gentaur's antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals. ** The preservative sodium azide is known to be poisonous and potentially hazardous to health. It should be handled only by trained staff. Despite of the product's low azide concentration it must be handled with care. Dispose according to regional rules!
• Other products
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• About
  Immunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures. Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by bio logo. Rabbit antibodies are very stable and can be stored for several days at room temperature. bio logo adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Group
  Polyclonals and antibodies
• Latin name
  Oryctolagus cuniculus

• Gene target
  Survivin   IAP  
• Gene symbol
  ALPI, CD47, IAPP, MAGT1, BIRC7
• Short name
  Research
• Technique
  Polyclonal, Rabbit, anti-, anti, IgG, antibody to, antibodies, IgGs, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Host
  Rabbit, Rabbits
• Isotype
  IgG, IgG
• Alternative name
  Survivin (IAP)
• Alternative technique
  polyclonals, rabbit-anti, antibodies, immunoglobulins

Gene info

• Identity
  HGNC:437
• Gene
  ALPI
• Long gene name
  alkaline phosphatase, intestinal
• Synonyms
  • IAP
• Synonyms name
  • intestinal alkaline phosphatase
• GenBank acession
  • M15694
• Locus
  2q37.1
• Discovery year
  1986-01-01
• Entrez gene record
  248
• Pubmed identfication
  • 3468508
  • 3469665
• RefSeq identity
  • NM_001631
• Classification
  • Alkaline phosphatases
• VEGA ID
  OTTHUMG00000133258

Gene info

• Identity
  HGNC:1682
• Gene
  CD47
• Long gene name
  CD47 molecule
• Synonyms gene
  • MER6
• Synonyms gene name
  • CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
• Synonyms
  • IAP
  • OA3
• Synonyms name
  • antigen identified by monoclonal antibody 1D8
  • antigenic surface determinant protein OA3
  • integrin associated protein
  • Rh-related antigen
  • leukocyte surface antigen CD47
  • CD47 glycoprotein
• Locus
  3q13.12
• Discovery year
  1994-12-12
• Entrez gene record
  961
• Pubmed identfication
  • 8294396
  • 2277087
• RefSeq identity
  • NM_001777
• Classification
  • CD molecules
  • Ig-like cell adhesion molecule family
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000044216

Gene info

• Identity
  HGNC:5329
• Gene
  IAPP
• Long gene name
  islet amyloid polypeptide
• Synonyms
  • AMYLIN
  • DAP
  • IAP
• Synonyms name
  • amylin
• Locus
  12p12.1
• Discovery year
  1989-05-24
• Entrez gene record
  3375
• RefSeq identity
  • NM_000415
• Classification
  • Neuropeptides
• VEGA ID
  OTTHUMG00000169128

Gene info

• Identity
  HGNC:28880
• Gene
  MAGT1
• Long gene name
  magnesium transporter 1
• Synonyms
  • DKFZp564K142
  • IAP
  • OST3B
  • MRX95
  • SLC58A1
• Synonyms name
  • oligosaccharyltransferase 3 homolog B (S. cerevisiae)
• Locus
  Xq21.1
• Discovery year
  2008-01-18
• Entrez gene record
  84061
• Pubmed identfication
  • 15804357
  • 25135935
• RefSeq identity
  • NM_032121
• Classification
  • Oligosaccharyltransferase complex subunits
  • Solute carriers
• VEGA ID
  OTTHUMG00000021882
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_353

Gene info

• Identity
  HGNC:13702
• Gene
  BIRC7
• Long gene name
  baculoviral IAP repeat containing 7
• Synonyms gene name
  • baculoviral IAP repeat-containing 7
• Synonyms
  • mliap
  • ML-IAP
  • KIAP
  • RNF50
• Synonyms name
  • melanoma inhibitor of apoptosis protein
  • kidney inhibitor of apoptosis protein
  • livin inhibitor-of-apoptosis
  • livin
• GenBank acession
  • AF301009
• Locus
  20q13.33
• Discovery year
  2001-03-06
• Entrez gene record
  79444
• Pubmed identfication
  • 11024045
  • 11162435
• RefSeq identity
  • NM_139317
• Classification
  • MicroRNA protein coding host genes
  • Ring finger proteins
  • Baculoviral IAP repeat containing
• VEGA ID
  OTTHUMG00000032957

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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