Rabbit PAI-1 (Biotin labeled latent fraction)[PAI-1]

Products_type

Protein
Products_gene_name

[PAI-1]
Properties

Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
Conjugation

Biotinylated
Description

FITC labelling for flow cytometry of antibodies and peptides.
Gene

Plasminogen activator inhibitor-1 (PAI-1) also known as endothelial plasminogen activator inhibitor or serpin E1 is a protein that in humans is encoded by the SERPINE1 gene. Elevated PAI-1 is a risk factor for thrombosis and atherosclerosis
About

Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Latin name

Oryctolagus cuniculus

Gene target

PAI-1 latent fraction [PAI-1]
Gene symbol

SERPINE1, SERPINB2, SERBP1, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR101-1, MIR1289-1
Short name

Rabbit PAI-1 ( latent fraction)[PAI-1]
Technique

Rabbit
Host

Rabbit, Rabbits
Label

Biotin
Alternative name

production species: rabbit PAI-1 (biotinilated labeled latent fraction)[PAI-1]
Alternative technique

rabbit-anti

Identity

HGNC:8583
Gene

SERPINE1
Long gene name

serpin family E member 1
Synonyms gene
- PLANH1
- PAI1
Synonyms gene name
- serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Synonyms
- PAI
Synonyms name
- plasminogen activator inhibitor, type I
GenBank acession
- M16006
Locus

7q22.1
Discovery year

1986-01-01
Entrez gene record

5054
Pubmed identfication
- 3097076
- 2891140
- 24172014
RefSeq identity
- NM_000602
Classification
- Serpin peptidase inhibitors
VEGA ID

OTTHUMG00000157107
Locus Specific Databases
- LRG_597

Identity

HGNC:8584
Gene

SERPINB2
Long gene name

serpin family B member 2
Synonyms gene
- PLANH2
- PAI2
Synonyms gene name
- serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2
- serpin peptidase inhibitor, clade B (ovalbumin), member 2
Synonyms
- HsT1201
- PAI-2
Synonyms name
- plasminogen-activator inhibitor
GenBank acession
- Y00630
Locus

18q21.33-q22.1
Discovery year

1989-02-07
Entrez gene record

5055
Pubmed identfication
- 24172014
RefSeq identity
- NM_002575
Classification
- Serpin peptidase inhibitors
VEGA ID

OTTHUMG00000060592

Identity

HGNC:5670
Gene

IGHVII-1-1
Long gene name

immunoglobulin heavy variable (II)-1-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
Synonyms
- IGHV(II)-1-1
GenBank acession
- AB019441
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28377
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152325

Identity

HGNC:5760
Gene

IGKV1OR2-1
Long gene name

immunoglobulin kappa variable 1/OR2-1 (pseudogene)
Synonyms gene
- IGKVPZ1
- IGKV1OR-1
Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
Synonyms
- IGKV1/OR-1
- IGKV1/OR2-1
GenBank acession
- Z12367
Locus

2p11.1
Discovery year

2000-04-18
Entrez gene record

3531
Pubmed identfication
- 2853098
Classification
- Immunoglobulin kappa (IGK) orphons
VEGA ID

OTTHUMG00000155081

Name

Drug Labeling
Concept

Scope note: Use of written, printed, or graphic materials upon or accompanying a drug container or wrapper. It includes contents, indications, effects, dosages, routes, methods, frequency and duration of administration, warnings, hazards, contraindications, side effects, precautions, and other relevant information.
Tree numbers
- E05.916.310
Qualifiers

trends, ethics, history, classification, economics, instrumentation, methods, standards, legislation & jurisprudence, statistics & numerical data