Rabbit anti Serine/Threonine-protein kinase PINK1 (C-Terminal)

• Catalog number
  X2760P
• Price
  Please ask
• Size
  100 μg

• Category
  Primary Antibodies
• Long description
  Protects against mitochondrial dysfunction during cellular stress, potentially by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). It is necessary for PARK2 recruitment to dysfunctional mitochondria to initiate their degradation. Defects in PINK1 are the cause of Parkinson disease type 6 (PARK6). A neurodegenerative disorder characterized by parkinsonian signs such as rigidity, resting tremor and bradykinesia. A subset of patients manifest additional symptoms including hyperreflexia, autonomic instability, dementia and psychiatric disturbances. Symptoms show diurnal fluctuation and can improve after sleep.
• Antibody come from
  n/a
• Other description
  Provided as solution in phosphate buffered saline with 0.08% sodium azide. Antigen Immunoaffiinity Purification
• Clone
  Polyclonal
• Antigen antibody binding interaction
  Rabbit anti Serine/Threonine-protein kinase PINK1 (C-Terminal) Antibody
• Antibody is raised in
  Rabbit
• Antibody s reacts with
  Human
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  Western blot, Immunohistochemistry, EIA
• Antibody s suited for
  Optimal concentration should be evaluated by serial dilutions.
• Storage
  -20ºC
• Relevant references
  no information yet
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Serine protease, D- or L-serine arginine rich enzyme of serine threonine kinase with serine that is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+ 3 form under biological conditions), a carboxyl group. It is non-essential in humans, meaning the body can synthesize it.
• About
  Rabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus

• Gene target
  Serine/Threonine-protein   kinase   PINK1  
• Gene symbol
  PINK1-AS, PINK1
• Short name
  Rabbit anti Serine/Threonine-protein kinase PINK1 (C-Terminal)
• Technique
  Rabbit, anti, antibody to
• Host
  Rabbit, Rabbits
• Isotype
  not specified
• Label
  unlabeled
• Alternative name
  production species: rabbit antibody to Serine/Threonine-protein phosphorylation catalyst phosphatase and tensin homolog induced putative kinase 1 (C-Terminal)
• Alternative technique
  rabbit-anti, antibodies
• Alternative to gene target
  PTEN induced putative kinase 1, PINK1 and IDBG-92922 and ENSG00000158828 and 65018, transferase activity, nuclei, Pink1 and IDBG-199773 and ENSMUSG00000028756 and 68943, PINK1 and IDBG-645657 and ENSBTAG00000006084 and 510683

Gene info

• Identity
  HGNC:38872
• Gene
  PINK1-AS
• Long gene name
  PINK1 antisense RNA
• Synonyms gene
  • PINK1-AS1
• Synonyms gene name
  • PINK1 antisense RNA 1 (non-protein coding)
  • PINK1 antisense RNA (non-protein coding)
• Synonyms
  • FLJ00387
  • PINK1AS
  • naPINK1
• GenBank acession
  • AK090466
• Locus
  1p36.12
• Discovery year
  2010-08-19
• Pubmed identfication
  • 17362513
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000002840

Gene info

• Identity
  HGNC:14581
• Gene
  PINK1
• Long gene name
  PTEN induced kinase 1
• Synonyms gene
  • PARK6
• Synonyms gene name
  • Parkinson disease (autosomal recessive) 6
  • PTEN induced putative kinase 1
• Synonyms
  • BRPK
• GenBank acession
  • AB053323
• Locus
  1p36.12
• Discovery year
  2001-02-08
• Entrez gene record
  65018
• Pubmed identfication
  • 24751536
  • 11494141
  • 15349860
  • 14607334
• RefSeq identity
  • NM_032409
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000002841
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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