Rabbit Anti-Human SLC6A8 Polyclonal: PE/ATTO 594
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Catalog numberSPC-1333D-P594
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PricePlease ask
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Size100 µl
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ImmunogenSynthesized peptide derived from C-terminal of human SLC6A8.
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Antibody s targetHuman SLC6A8
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Antibody s full descriptionRabbit Anti-Human SLC6A8 Polyclonal
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Primary research fieldsCell Signaling
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Antibody s categoryPolyclonal Antibodies
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Antibody s other nameSLC6A 8 Antibody, Creatine transporter 1 Antibody, CRTR Antibody, CT1 Antibody, Sodium and chloride-dependent creatine transporter 1 Antibody, Solute carrier family 6 member 8 Antibody
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Verified applicationsWB, ELISA
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Raised inRabbit
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Antibody s reactivityHuman, Mouse, Rat
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Antibody s recommended dilutions for useWB (1:1000), ELISA (1:10000); optimal dilutions for assays should be determined by the user.
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Antibody s purified fromPeptide Affinity Purified
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Recommended buffer for storagePBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide
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Antibody s concentrationSee included datasheet or contact our support service
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Antibody s specificityDetects ~70kDa, endogenous levels of total SLC6A8 protein.
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Storage recommendations-20°C
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Shipping recommendationsBlue Ice or 4°C
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Certificate of analysisA 1:1000 dilution of SPC-1333 was sufficient for detection of SLC6A8 in 10 µg of HuvEc cell lysates by ECL immunoblot analysis using Goat Anti-Rabbit IgG:HRP as the secondary antibody.
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Antibody in cellMembrane
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Tissue specificityPredominantly expressed in skeletal muscle and kidney. Also found in brain, heart, colon, testis and prostate.
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Scientific contextSLC6A8 is required for the uptake of creatine in muscles and brain. Deficiency of this gene is an X-linked form of intellectual diavility and is the most common casue of cerebral creatine syndromes.
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Bibliography1. more
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Released date6/Sep/2016
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NCBI numberNP_005620.1
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Gene number6535
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Protein numberP48029
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PubMed numberRefer to PubMed
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Tested applicationsTo be tested
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Tested reactivityTo be tested
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Antibody s datasheetContact our support service to receive datasheet or other technical documentation.
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Representative figure legendWestern blot analysis of Human HuvEc cell lysates showing detection of ~70kDa SLC6A8 protein using Rabbit Anti-SLC6A8 Polyclonal Antibody (SPC-1333). Lane 1: Human HUVEC cells. Lane 2: Human HUVEC cells treated with the immunizing peptide. Primary Antibody: Rabbit Anti-SLC6A8 Polyclonal Antibody (SPC-1333) at 1:1000. Predicted/Observed Size: ~70kDa. Rabbit Anti-SLC6A8 Antibody used in Western blot (WB) on HuvEc cell lysates (SPC-1333)
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Warning informationNon-hazardous
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Country of productionCanada
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Total weight kg1.4
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Net weight g0.1
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Stock availabilitIn Stock
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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TestStressMark antibodies supplies antibodies that are for research of human proteins.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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GroupPolyclonals and antibodies
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AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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Gene target
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Gene symbolSLC6A8
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Short nameRabbit Anti- SLC6A8 Polyclonal: PE/ATTO 594
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Techniqueanti-Human, Polyclonal, Rabbit, anti-, anti, antibody to, antibodies, antibodies against human proteins, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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HostRabbit, Rabbits
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IsotypeIgG
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LabelPE/ATTO 594
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SpeciesHuman, Humans
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Alternative nameproduction species: rabbit Antibody toHuman SLC6A8 polyclonal: peroxidase/ATTO 594
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Alternative techniquepolyclonals, rabbit-anti, antibodies
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Gene info
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Identity
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Gene
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Long gene namesolute carrier family 6 member 8
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Synonyms gene name
- solute carrier family 6 (neurotransmitter transporter, creatine), member 8
- solute carrier family 6 (neurotransmitter transporter), member 8
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Synonyms
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Synonyms name
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Locus
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Discovery year1994-12-19
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Entrez gene record
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Pubmed identfication
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Classification
- Solute carriers
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data