Rabbit Anti-Human NDR1 (pSer281+pThr282) Polyclonal: Streptavidin
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Catalog numberSPC-1035D-STR
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PricePlease ask
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Size100 µl
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ImmunogenA phospho-specific peptide corresponding to residues surrounding Ser281 and Thr282 of human NDR1 (AA278-285)
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Antibody s targetHuman NDR1 (pSer281+pThr282)
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Antibody s full descriptionRabbit Anti-Human NDR1 (pSer281+pThr282) Polyclonal
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Antibody s categoryPolyclonal Antibodies
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Antibody s other nameNDR 1 antibody, NDR antibody, Ndr Ser/Thr kinase-like protein antibody, NDR1 antibody, NDR1 protein kinase antibody, Nuclear Dbf2 related kinase 1 antibody, Serine/threonine protein kinase 38 antibody, STK 38 antibody, STK38 antibody, STK38_HUMAN antibody
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Verified applicationsWB, AM
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Raised inRabbit
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Antibody s reactivityHuman
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Antibody s recommended dilutions for useWB (1:250); optimal dilutions for assays should be determined by the user.
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Antibody s purified fromPeptide Affinity Purified
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Recommended buffer for storagePBS pH7.4, 50% glycerol, 0.025% Thimerosal
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Antibody s concentrationSee included datasheet or contact our support service
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Antibody s specificityDetects 54.19 kDa.
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Storage recommendations-20°C
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Shipping recommendationsBlue Ice or 4°C
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Certificate of analysisA 1:250 dilution of SPC-1035 was sufficient for detection of NDR1 (pSer281+pThr282) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
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Antibody in cellNucleus, Cytoplasm
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Tissue specificityUbiquitously expressed with highest levels observed in peripheral blood leukocytes.
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Scientific contextSTK38 is a negative regulator of MAP3K1/2 signalling. Converts MAP3K2 from its phosphorylated form to its nonphosphorylated form and inhibits autophosphorylation of MAP3K2. The MAPK/ERK pathway has been implicated in oncogenesis as either a promoter or inhibitor depending on the cancer system. Thus, the role of STK38 in cancer is likely highly contextual.
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BibliographyRefer to PubMed
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Released date29/Aug/2016
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NCBI numberNP_009202
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Gene number11329
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Protein numberQ15208
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PubMed numberRefer to PubMed
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Tested applicationsTo be tested
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Tested reactivityTo be tested
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Antibody s datasheetContact our support service to receive datasheet or other technical documentation.
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Representative figure linkNo Data Available
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Warning informationNon-hazardous
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Country of productionCanada
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Total weight kg1.4
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Net weight g0.1
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Stock availabilitIn Stock
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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TestStressMark antibodies supplies antibodies that are for research of human proteins.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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GroupPolyclonals and antibodies
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AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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Gene target
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Gene symbolSTK38, NDRG1
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Short nameRabbit Anti- NDR1 (pSer281+pThr282) Polyclonal: Streptavidin
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Techniqueanti-Human, Polyclonal, Rabbit, anti-, anti, antibody to, antibodies, antibodies against human proteins, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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HostRabbit, Rabbits
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IsotypeImmunoglobulin
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LabelStreptavidin
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SpeciesHuman, Humans
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Alternative nameproduction species: rabbit Antibody toHuman NDR1 (pSer281andpThr282) polyclonal: biotinilated-binding streptavidin
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Alternative techniquepolyclonals, rabbit-anti, antibodies
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Gene info
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Identity
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Gene
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Long gene nameserine/threonine kinase 38
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Synonyms
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Synonyms name
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Locus
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Discovery year2001-12-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- AGC family kinases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameN-myc downstream regulated 1
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Synonyms gene
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-23
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Entrez gene record
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Pubmed identfication
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Classification
- NDRG family
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data