Rabbit Anti-Human FRK (pTyr387) Polyclonal: Streptavidin

  • Catalog number
    SPC-984D-STR
  • Price
    Please ask
  • Size
    100 µl
  • Immunogen
    A phospho-specific peptide corresponding to residues surrounding Tyr387 of human FRK (AA384-390)
  • Antibody s target
    Human FRK (pTyr387)
  • Antibody s full description
    Rabbit Anti-Human FRK (pTyr387) Polyclonal
  • Antibody s category
    Polyclonal Antibodies
  • Antibody s other name
    Beta cell Src homology tyrosine kinase Antibody, FRK Antibody, BSK Antibody, BSK/IYK Antibody, C85044 Antibody, Frk fyn related kinase Antibody, FRK_HUMAN Antibody, FYN related kinase Antibody, GASK Antibody, Gastrointestinal associated kinase Antibody, GTK Antibody, Intestine tyrosine kinase Antibody, Nuclear tyrosine protein kinase RAK Antibody, Protein-tyrosine kinase 5 Antibody, PTK5 Antibody, RAK Antibody,Tyrosine protein kinase FRK Antibody
  • Verified applications
    WB, AM
  • Raised in
    Rabbit
  • Antibody s reactivity
    Human
  • Antibody s recommended dilutions for use
    WB (1:250); optimal dilutions for assays should be determined by the user.
  • Antibody s purified from
    Peptide Affinity Purified
  • Recommended buffer for storage
    PBS pH7.4, 50% glycerol, 0.025% Thimerosal
  • Antibody s concentration
    See included datasheet or contact our support service
  • Antibody s specificity
    Detects 58.254 kDa.
  • Storage recommendations
    -20°C
  • Shipping recommendations
    Blue Ice or 4°C
  • Certificate of analysis
    A 1:250 dilution of SPC-984 was sufficient for detection of FRK (pTyr387) in 10 µg of 293T cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
  • Antibody in cell
    Cytoplasm, Nucleus
  • Tissue specificity
    Highly expressed in epithelial derived cell lines and tissues, especially normal liver, kidney, breast and colon
  • Scientific context
    FRK is a protein-tyrosine kinase. It is involved in positive regulation of PTEN by increasing its stability and preventing degradation and negative regulation of cell proliferation. It may also have functions during G1 and S phase in the nucleus to suppress growth.
  • Bibliography
    Refer to PubMed
  • Released date
    29/Aug/2016
  • NCBI number
    NP_002022
  • Gene number
    2444
  • Protein number
    P42685
  • PubMed number
    Refer to PubMed
  • Tested applications
    To be tested
  • Tested reactivity
    To be tested
  • Antibody s datasheet
    Contact our support service to receive datasheet or other technical documentation.
  • Representative figure link
    No Data Available
  • Warning information
    Non-hazardous
  • Country of production
    Canada
  • Total weight kg
    1.4
  • Net weight g
    0.1
  • Stock availabilit
    In Stock
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Test
    StressMark antibodies supplies antibodies that are for research of human proteins.
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Group
    Polyclonals and antibodies
  • About
    Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
  • Latin name
    Oryctolagus cuniculus
  • Gene target
  • Gene symbol
    FRK
  • Short name
    Rabbit Anti- FRK (pTyr387) Polyclonal: Streptavidin
  • Technique
    anti-Human, Polyclonal, Rabbit, anti-, anti, antibody to, antibodies, antibodies against human proteins, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
  • Host
    Rabbit, Rabbits
  • Isotype
    Immunoglobulin
  • Label
    Streptavidin
  • Species
    Human, Humans
  • Alternative name
    production species: rabbit Antibody toHuman FYN oncogene related to v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian), FGR, YES-related kinase (pTyr387) polyclonal: biotinilated-binding streptavidin
  • Alternative technique
    polyclonals, rabbit-anti, antibodies
  • Alternative to gene target
    fyn-related kinase, GTK and PTK5 and RAK, FRK and IDBG-95607 and ENSG00000111816 and 2444, transferase activity, nuclei, Frk and IDBG-143883 and ENSMUSG00000019779 and 14302, FRK and IDBG-631180 and ENSBTAG00000020018 and 509227
Gene info
  • Identity
  • Gene
    FRK
  • Long gene name
    fyn related Src family tyrosine kinase
  • Synonyms gene
  • Synonyms gene name
    • PTK5 protein tyrosine kinase 5
    • fyn-related kinase
    • fyn-related Src family tyrosine kinase
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1995-02-08
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Src family tyrosine kinases
    • SH2 domain containing
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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