Rabbit Anti-Human DUSP3 Polyclonal: ATTO 655

  • Catalog number
    SPC-1123D-A655
  • Price
    Please ask
  • Size
    100 µl
  • Immunogen
    A synthetic peptide of human DUSP3 (AA 144-158)
  • Antibody s target
    Human DUSP3
  • Antibody s full description
    Rabbit Anti-Human DUSP3 Polyclonal
  • Antibody s category
    Polyclonal Antibodies
  • Antibody s other name
    Dual specificity phosphatase 3 antibody, Dual specificity protein phosphatase 3 antibody, Dual specificity protein phosphatase VHR antibody, DUS3_HUMAN antibody, DUSP3 antibody, Serine/threonine specific protein phosphatase antibody, Vaccinia H1-related phosphatase antibody, Vaccinia virus phosphatase VH1 related antibody, VHR antibody
  • Verified applications
    WB, AM
  • Raised in
    Rabbit
  • Antibody s reactivity
    Human, Mouse
  • Antibody s recommended dilutions for use
    WB (1:250); optimal dilutions for assays should be determined by the user.
  • Antibody s purified from
    Peptide Affinity Purified
  • Recommended buffer for storage
    PBS pH7.4, 50% glycerol, 0.025% Thimerosal
  • Antibody s concentration
    See included datasheet or contact our support service
  • Antibody s specificity
    Detects 20.478 kDa.
  • Storage recommendations
    -20°C
  • Shipping recommendations
    Blue Ice or 4°C
  • Certificate of analysis
    A 1:250 dilution of SPC-1123 was sufficient for detection of DUSP3 in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
  • Antibody in cell
    Nucleus
  • Tissue specificity
    See included datasheet or contact our support service.
  • Scientific context
    DUSP3 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.
  • Bibliography
    Refer to PubMed
  • Released date
    29/Aug/2016
  • NCBI number
    NP_004081
  • Gene number
    1845
  • Protein number
    P51452
  • PubMed number
    Refer to PubMed
  • Tested applications
    To be tested
  • Tested reactivity
    To be tested
  • Antibody s datasheet
    Contact our support service to receive datasheet or other technical documentation.
  • Representative figure link
    No Data Available
  • Warning information
    Non-hazardous
  • Country of production
    Canada
  • Total weight kg
    1.4
  • Net weight g
    0.1
  • Stock availabilit
    In Stock
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Test
    StressMark antibodies supplies antibodies that are for research of human proteins.
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Group
    Polyclonals and antibodies
  • About
    Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
  • Latin name
    Oryctolagus cuniculus
  • Gene target
    DUSP3   ATTO   655  
  • Gene symbol
    DUSP3
  • Short name
    Rabbit Anti- DUSP3 Polyclonal: ATTO 655
  • Technique
    anti-Human, Polyclonal, Rabbit, anti-, anti, antibody to, antibodies, antibodies against human proteins, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
  • Host
    Rabbit, Rabbits
  • Isotype
    Immunoglobulin
  • Label
    ATTO 655
  • Species
    Human, Humans
  • Alternative name
    production species: rabbit Antibody toHuman dual specificity phosphatase 3 polyclonal: ATTO 655
  • Alternative technique
    polyclonals, rabbit-anti, antibodies
  • Alternative to gene target
    dual specificity phosphatase 3, VHR, DUSP3 and IDBG-52945 and ENSG00000108861 and 1845, MAP kinase phosphatase activity, nuclei, Dusp3 and IDBG-212400 and ENSMUSG00000003518 and 72349, DUSP3 and IDBG-640759 and ENSBTAG00000003966 and 615432
Gene info
  • Identity
  • Gene
  • Long gene name
    dual specificity phosphatase 3
  • Synonyms gene
  • Synonyms gene name
    • vaccinia virus phosphatase VH1-related
  • GenBank acession
  • Locus
  • Discovery year
    1994-05-19
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Atypical dual specificity phosphatases
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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