Rabbit Anti-Human DUSP11 Polyclonal: RPE
-
Catalog numberSPC-1119D-RPE
-
PricePlease ask
-
Size100 µl
-
-
ImmunogenA synthetic peptide of human DUSP11 (AA 290-304)
-
Antibody s targetHuman DUSP11
-
Antibody s full descriptionRabbit Anti-Human DUSP11 Polyclonal
-
Antibody s categoryPolyclonal Antibodies
-
Antibody s other nameDual specificity phosphatase 11 antibody, Dual specificity protein phosphatase 11 antibody, DUS11_HUMAN antibody, DUSP11 antibody, Phosphatase that interacts with RNA/RNP complex 1 antibody, PIR1 antibody, RNA/RNP complex 1 interacting antibody, RNA/RNP complex interacting phosphatase antibody
-
Verified applicationsWB, AM
-
Raised inRabbit
-
Antibody s reactivityHuman, Mouse
-
Antibody s recommended dilutions for useWB (1:250); optimal dilutions for assays should be determined by the user.
-
Antibody s purified fromPeptide Affinity Purified
-
Recommended buffer for storagePBS pH7.4, 50% glycerol, 0.025% Thimerosal
-
Antibody s concentrationSee included datasheet or contact our support service
-
Antibody s specificityDetects ~38kDa.
-
Storage recommendations-20°C
-
Shipping recommendationsBlue Ice or 4°C
-
Certificate of analysisA 1:250 dilution of SPC-1119 was sufficient for detection of DUSP11 in 10 µg of human kidney lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
-
Antibody in cellNucleus
-
Tissue specificityTestis
-
Scientific contextDUSP11 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism.
-
BibliographyRefer to PubMed
-
Released date29/Aug/2016
-
NCBI numberNP_003575
-
Gene number8446
-
Protein numberO75319
-
PubMed numberRefer to PubMed
-
Tested applicationsTo be tested
-
Tested reactivityTo be tested
-
Antibody s datasheetContact our support service to receive datasheet or other technical documentation.
-
Representative figure linkNo Data Available
-
Warning informationNon-hazardous
-
Country of productionCanada
-
Total weight kg1.4
-
Net weight g0.1
-
Stock availabilitIn Stock
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
TestStressMark antibodies supplies antibodies that are for research of human proteins.
-
PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
GroupPolyclonals and antibodies
-
AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
-
Latin nameOryctolagus cuniculus
-
Gene target
-
Gene symbolRPE, DUSP11
-
Short nameRabbit Anti- DUSP11 Polyclonal: RPE
-
Techniqueanti-Human, Polyclonal, Rabbit, anti-, anti, antibody to, antibodies, antibodies against human proteins, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
-
HostRabbit, Rabbits
-
IsotypeImmunoglobulin
-
LabelRPE
-
SpeciesHuman, Humans
-
Alternative nameproduction species: rabbit Antibody toHuman DUSP11 polyclonal: RPE
-
Alternative techniquepolyclonals, rabbit-anti, antibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameribulose-5-phosphate-3-epimerase
-
Locus
-
Discovery year2001-06-22
-
Entrez gene record
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namedual specificity phosphatase 11
-
Synonyms gene name
- dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1998-11-06
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Atypical dual specificity phosphatases
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data