Rabbit anti DICER1

• Catalog number
  X2756P
• Price
  Please ask
• Size
  100 μg

• Category
  Primary Antibodies
• Long description
  Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto EIF2C2/AGO2. EIF2C2/AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. Also cleaves double-stranded RNA to produce short interfering RNAs (siRNAs) which target the selective destruction of complementary RNAs.
• Antibody come from
  n/a
• Other description
  Provided as solution in phosphate buffered saline with 0.08% sodium azide. Antigen Immunoaffiinity Purification
• Clone
  Polyclonal
• Antigen antibody binding interaction
  Rabbit anti DICER1 Antibody
• Antibody is raised in
  Rabbit
• Antibody s reacts with
  Human
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  Western blot, Immunohistochemistry, EIA
• Antibody s suited for
  Optimal concentration should be evaluated by serial dilutions.
• Storage
  -20ºC
• Relevant references
  no information yet
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• About
  Rabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus

• Gene target
  DICER1  
• Gene symbol
  DICER1-AS1, DICER1
• Short name
  Rabbit anti DICER1
• Technique
  Rabbit, anti, antibody to
• Host
  Rabbit, Rabbits
• Isotype
  not specified
• Label
  unlabeled
• Alternative name
  production species: rabbit antibody to DICER1
• Alternative technique
  rabbit-anti, antibodies

Gene info

• Identity
  HGNC:43017
• Gene
  DICER1-AS1
• Long gene name
  DICER1 antisense RNA 1
• Synonyms gene
  • DICER1-AS
• Synonyms gene name
  • DICER1 antisense RNA (non-protein coding)
• Synonyms
  • FLJ45244
• Synonyms name
  • DICER1 antisense RNA (non-protein coding)
• GenBank acession
  • BC040596
• Locus
  14q32.13
• Discovery year
  2011-09-16
• Entrez gene record
  400242
• Pubmed identfication
  • 29772430
• RefSeq identity
  • NR_015415
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000150190

Gene info

• Identity
  HGNC:17098
• Gene
  DICER1
• Long gene name
  dicer 1, ribonuclease III
• Synonyms gene
  • MNG1
• Synonyms gene name
  • Dicer1, Dcr-1 homolog (Drosophila)
  • multinodular goitre 1
  • dicer 1, ribonuclease type III
• Synonyms
  • Dicer
  • KIAA0928
  • K12H4.8-LIKE
  • HERNA
• Synonyms name
  • dicer 1, double-stranded RNA-specific endoribonuclease
• GenBank acession
  • AB028449
• Locus
  14q32.13
• Discovery year
  2002-05-09
• Entrez gene record
  23405
• Pubmed identfication
  • 10051563
  • 10786632
  • 21205968
• RefSeq identity
  • NM_030621
• Classification
  • RISC loading complex
  • Endoribonucleases
  • RNA helicases
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000166134
• Locus Specific Databases
  • LRG_492

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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