(R)-Perharidine-1
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Catalog number2615-5
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PricePlease ask
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Size5 mg
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Alternative_name(R)-2-((3-Isopropyl)-7-(4-pyridin-2-yl)benzylamino)-3H-imidazo[4,5-b]pyridine-5-yl)amino)butan-1-ol
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Description(R)-Perharidine-1 is a potent and selective inhibitor of cyclin dependent kinases CDK1, CDK2, CDK5 and CDK9. Apoptosis inducer . Also acts as a casein kinase 1 (CK1δ/ε) inhibitor. Inhibits the proliferation of various cancer cell lines.
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CAS Number1133437-80-5
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Structure AvailableY
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Salt FormNo
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Molecular FormulaC₂₅H₃₀N₆O
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Molecular Weight430.55
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Cell PermeableYes
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Purity>95% by NMR
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SolubilitiesDMSO or EtOH
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HandlingProtect from air and light
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Tag LineA potent CDK inhibitor
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Storage Condition-20 ̊C
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Shipping ConditionGel pack
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Shelf Life36 months
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SMILESCC[C@H](CO)NC1=CC(NCC2=CC=C(C3=NC=CC=C3)C=C2)=C4C(N(C(C)C)C=N4)=N1
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InChiInChI=1S/C25H30N6O/c1-4-20(15-32)29-23-13-22(24-25(30-23)31(16-28-24)17(2)3)27-14-18-8-10-19(11-9-18)21-7-5-6-12-26-21/h5-13,16-17,20,32H,4,14-15H2,1-3H3,(H2,27,29,30)/t20-/m1/s1
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InChi KeyVGHHVXRBOQENRA-HXUWFJFHSA-N
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MSDS AvailableYes
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Gene target
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Short name(R)-Perharidine-1
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Alternative name(R)-Perharidine-1
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