PX-866
-
Catalog number1965-1
-
PricePlease ask
-
Size1 mg
-
-
Alternative_nameDJM-166; DJM-2-166
-
DescriptionCell-permeable. A derivative of Wortmannin (Cat. No. 1670-1), that potently and irreversibly inhibits PI 3-kinase with selectivity for p110⍺ (IC₅₀ = 0.1 nM). Displays antitumor activity.
-
CAS Number502632-66-8
-
Structure AvailableYes
-
Salt FormNo
-
Molecular FormulaC₂₉H₃₅NO₈
-
Molecular Weight525.59
-
Cell PermeableYes
-
Purity≥98% by TLC
-
SolubilitiesDMSO (~ 25 mg/ml)
-
HandlingProtect from light and air
-
Tag LineA potent PI3 Kinase inhibitor
-
Storage Condition-20°C
-
Shipping Conditiongel pack
-
Shelf Life48 months
-
MDL NumberMFCD07784511
-
PubChem CID9849735
-
SMILESCC(=O)OC1CC2(C(CCC2=O)C3=C1C4(C(OC(=O)C(=CN(CC=C)CC=C)C4=C(C3=O)O)COC)C)C
-
InChiInChI=1S/C29H35NO8/c1-7-11-30(12-8-2)14-17-23-26(34)25(33)22-18-9-10-20 (32)28(18,4)13-19(37-16(3)31)24(22)29(23,5)21(15-36-6)38-27(17)35/h7-8, 14,18-19,21,34H,1-2,9-13,15H2,3-6H3/b17-14+/t18-,19+,21+,28-,29-/m0/s1
-
InChi KeyQIUASFSNWYMDFS-NILGECQDSA-N
-
MSDS AvailableYes
-
Gene target
-
Short namePX-866
-
Alternative namePX-866
-