PUMA (CT) Polyclonal Antibody

• Catalog number
  MBS194335
• Price
  Please ask
• Size
  100ug

• Alternative name1
  Anti-PUMA (CT) Polyclonal Antibody
• Alternative name2
  PUMA (CT) PAb
• Alternative name3
  PUMA (CT) Polyclonal Antibody
• Alternative name4
  PUMA (CT)
• Alternative name5
  PUMA (CT)
• Other names
  PUMA; Bcl-2-binding component 3; bcl-2-binding component 3; p53 up-regulated modulator of apoptosis; Bcl-2 binding component 3; p53 up-regulated modulator of apoptosis
• Gene name
  N/A
• Gene name synonims
  N/A
• Other gene names
  Bbc3; Bbc3; Puma; Puma
• Category
  Antibodies
• Clonality
  Polyclonal
• Immunoglobulin isotype
  N/A
• Clone
  Polyclonal antibody
• Host organism
  Rabbit
• Species reactivity
  N/A
• Specificity and cross reactivity
  PUMA (CT) [This rabbit antibody recognizes an epitope of aa 180-193 at the C-terminus of human and mouse PUMA (p53 Upregulated Modulator of Apoptosis).] This antibody recognizes an epitope at the C-terminus of human and mouse PUMA (p53 Upregulated Modulator of Apoptosis). PUMA is a pro-apoptotic Bcl-2 family member that encodes two BH3 domain-containing proteins, PUMA- alpha and PUMA- beta . PUMA proteins bind Bcl-2, localize to mitochondria, and induce cytochrome c release and apoptosis in response to p53.
• Purification method
  N/A
• Form Appearance
  100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
• Concentration
  N/A
• Storage and shipping
  productone is stable for at least one (1) year productone should be stored at -20 degrees Celsius.. Avoid multiple freeze-thaw cycles.
• Tested for
  Immunoblot
• Description
  productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
• Advisory
  In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Properties
  If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  PUMA  
• Gene symbol
  BBC3, HCAR2
• Short name
  PUMA (CT) Polyclonal Antibody
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Alternative name
  PUMA (CT) polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:17868
• Gene
  BBC3
• Long gene name
  BCL2 binding component 3
• Synonyms
  • JFY1
  • PUMA
• Synonyms name
  • p53-upregulated modulator of apoptosis
• GenBank acession
  • AF332558
• Locus
  19q13.32
• Discovery year
  2002-07-22
• Entrez gene record
  27113
• Pubmed identfication
  • 11463392
  • 11572983
• RefSeq identity
  • NM_014417
• Classification
  • BCL2 homology region 3 (BH3) only
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000183489

Gene info

• Identity
  HGNC:24827
• Gene
  HCAR2
• Long gene name
  hydroxycarboxylic acid receptor 2
• Synonyms gene
  • GPR109A
• Synonyms gene name
  • G protein-coupled receptor 109A
• Synonyms
  • HCA2
  • HM74A
  • PUMAG
  • Puma-g
  • NIACR1
• Synonyms name
  • niacin receptor 1
• GenBank acession
  • AY148884
• Locus
  12q24.31
• Discovery year
  2004-04-22
• Entrez gene record
  338442
• Pubmed identfication
  • 21167710
  • 12522134
  • 12646212
  • 19141678
  • 18983141
  • 21454438
• RefSeq identity
  • NM_177551
• Classification
  • Hydroxycarboxylic acid receptors
• VEGA ID
  OTTHUMG00000162722

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products