PTPN11 (Tyr584) Antibody
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Catalog numberbs-3405R
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PricePlease ask
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Size0.1ml
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Long namePTPN11 (Tyr584) Primary Polyclonal Antibody
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Also known asPTPN11 (Tyr584) PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenPTPN11 Tyr584
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SpecificityThis is a highly specific antibody against PTPN11 Tyr584. This phosphorylation site is homologous across the listed cross reactive species.
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Modification sPhosphorylation
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Modification site sTyr584
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range550-597/597
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Subcellular locationCytoplasm
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SourceKLH conjugated synthetic phosphopeptide derived from human PTPN11 around the phosphorylation site of Tyr584
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Gene ID number5781
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Swiss ProtQ06124
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenActs downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesCFC; NS1; SHP2; BPTP3; PTP2C; PTP-1D; SH-PTP2; SH-PTP3; Tyrosine-protein phosphatase non-receptor type 11; Protein-tyrosine phosphatase 1D; Protein-tyrosine phosphatase 2C; PTP-2C; SHP-2; PTPN11; SHPTP2
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolPTPN11
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Short nameAnti-PTPN11 Tyr584
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative namePTPN11 (Tyr584) Polyclonal Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameprotein tyrosine phosphatase non-receptor type 11
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Synonyms gene
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Synonyms gene name
- Noonan syndrome 1
- protein tyrosine phosphatase, non-receptor type 11
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1993-03-03
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Entrez gene record
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Pubmed identfication
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Classification
- Protein tyrosine phosphatases non-receptor type
- SH2 domain containing
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data