Sphingosine Kinase 2 antibody Long Form N Terminal HIS Tag - Active Enzyme

• Catalog number
  X1840E
• Price
  Please ask
• Size
  10 μg

• Category
  Proteins & Peptides
• Long description
  The long form of sphingosine kinase 2 (Sphk2-L) is a species-specific isoform of the Sphk2 enzyme expressed in human but not in mouse. It is an N-terminal extended form of Sphk2, extended by 36 amino acids. It functions as expected, catalyzing the formation of sphingosine 1-phosphate from sphingosine, however it appears to have a decreased ability to inhibit DNA synthesis as compared to Sphk2-S (short form of Sphk2). Under normal cellular conditions, Sphk2-L does not appear to inhibit DNA synthesis, but under serum deprivation, SphK2-L translocates to the nucleus and accumlates. This accumlation may be involved in the cessation of cell proliferation or apoptosis depending on the cell type.
• Antibody come from
  n/a
• Other description
  Provided as solution in phosphate buffered saline with 0.08% sodium azide.
• Clone
  not specified
• Antigen antibody binding interaction
  Sphingosine Kinase 2 antibody Long Form N Terminal HIS Tag - Active Enzyme
• Antibody is raised in
  Sf9 cells
• Antibody s reacts with
  Human
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  Study of enzyme kinetics, screening inhibitors, and selectivity profiling.
• Antibody s suited for
  Blocking peptide for use with SIAH1 antibodies (Cat. Nos. X1859P & X1864P).
• Storage
  -80ºC
• Relevant references
  no information yet
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Properties
  If you buy Antibodies supplied by nordc they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Description
  Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
• Conjugation
  histidine
• French translation
  anticorps

• Gene target
  Sphingosine   Kinase   Long   Form   Terminal   HIS   Tag   Active  
• Gene symbol
  HAL, VIS1, AKR1B10, TRH-GTG1-1, TRH-GTG1-3, TRH-GTG2-1, TRH-GTG3-1, TRH-GTG1-2, TRH-GTG1-4, TRH-GTG1-5
• Short name
  Sphingosine Kinase 2 antibody Long Form N Terminal HIS Tag - Active Enzyme
• Technique
  Antibody, Enzyme, antibodies against human proteins, antibodies for, enzymes, Tags
• Isotype
  not specified
• Label
  unlabeled
• Alternative name
  Sphingosine phosphorylation catalyst 2 (antibody to-) large Form N Terminal histidine detection labelled - functionnal Enzyme
• Alternative technique
  antibodies, enzymes

Gene info

• Identity
  HGNC:4806
• Gene
  HAL
• Long gene name
  histidine ammonia-lyase
• Synonyms gene
  • HIS
• Locus
  12q23.1
• Discovery year
  1988-08-31
• Entrez gene record
  3034
• VEGA ID
  OTTHUMG00000170354

Gene info

• Identity
  HGNC:12696
• Gene
  VIS1
• Long gene name
  viral integration site 1
• Synonyms
  • HIS1
  • HIS-1
• GenBank acession
  • U56440
• Locus
  2q14-q21
• Discovery year
  1992-11-25
• Entrez gene record
  7435
• Pubmed identfication
  • 1682866

Gene info

• Identity
  HGNC:382
• Gene
  AKR1B10
• Long gene name
  aldo-keto reductase family 1 member B10
• Synonyms gene
  • AKR1B11
• Synonyms gene name
  • aldo-keto reductase family 1, member B10 (aldose reductase)
• Synonyms
  • AKR1B12
  • ARL-1
  • HIS
  • ARL1
  • HSI
  • ALDRLn
• Synonyms name
  • aldose reductase-like 1
  • aldo-keto reductase family 1, member B11 (aldose reductase-like)
  • aldose reductase-like peptide
  • aldose reductase-related protein
  • small intestine reductase
• GenBank acession
  • AF052577
• Locus
  7q33
• Discovery year
  2000-08-24
• Entrez gene record
  57016
• Pubmed identfication
  • 9765596
  • 9565553
• RefSeq identity
  • NM_020299
• Classification
  • Aldo-keto reductases
• VEGA ID
  OTTHUMG00000155356

Gene info

• Identity
  HGNC:34535
• Gene
  TRH-GTG1-1
• Long gene name
  tRNA-His (anticodon GTG) 1-1
• Synonyms gene
  • TRNAH4
• Synonyms gene name
  • transfer RNA histidine 4 (anticodon GUG)
  • transfer RNA-His (GTG) 1-1
• Synonyms
  • tRNA-His-GTG-1-1
• GenBank acession
  • HG983832
• Locus
  1q21.1
• Discovery year
  2008-08-21
• Entrez gene record
  100188991
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34874
• Gene
  TRH-GTG1-3
• Long gene name
  tRNA-His (anticodon GTG) 1-3
• Synonyms gene
  • TRNAH9
• Synonyms gene name
  • transfer RNA histidine 9 (anticodon GUG)
  • transfer RNA-His (GTG) 1-3
• Synonyms
  • tRNA-His-GTG-1-3
• GenBank acession
  • HG983834
• Locus
  1q21.2
• Discovery year
  2008-08-29
• Entrez gene record
  100189307
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34918
• Gene
  TRH-GTG2-1
• Long gene name
  tRNA-His (GTG) 2-1
• Synonyms gene
  • TRNAH11
• Synonyms gene name
  • transfer RNA histidine 11 (anticodon GUG)
  • transfer RNA-His (GTG) 2-1
• Synonyms
  • tRNA-His-GTG-2-1
• GenBank acession
  • HG983841
• Locus
  1
• Discovery year
  2008-08-29
• Entrez gene record
  100189350
• Classification
  • Low confidence cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34805
• Gene
  TRH-GTG3-1
• Long gene name
  tRNA-His (anticodon GTG) 3-1
• Synonyms gene
  • TRNAH8
• Synonyms gene name
  • transfer RNA histidine 8 (anticodon GUG)
  • transfer RNA-His (GTG) 3-1
• Synonyms
  • tRNA-His-GTG-3-1
• GenBank acession
  • HG983842
• Locus
  3q24
• Discovery year
  2008-08-29
• Entrez gene record
  100189242

Gene info

• Identity
  HGNC:34902
• Gene
  TRH-GTG1-2
• Long gene name
  tRNA-His (anticodon GTG) 1-2
• Synonyms gene
  • TRNAH10
• Synonyms gene name
  • transfer RNA histidine 10 (anticodon GUG)
  • transfer RNA-His (GTG) 1-2
• Synonyms
  • tRNA-His-GTG-1-2
• GenBank acession
  • HG983833
• Locus
  1q21.1
• Discovery year
  2008-08-29
• Entrez gene record
  100189334
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34736
• Gene
  TRH-GTG1-4
• Long gene name
  tRNA-His (anticodon GTG) 1-4
• Synonyms gene
  • TRNAH7
• Synonyms gene name
  • transfer RNA histidine 7 (anticodon GUG)
  • transfer RNA-His (GTG) 1-4
• Synonyms
  • tRNA-His-GTG-1-4
• GenBank acession
  • HG983835
• Locus
  1q21.2
• Discovery year
  2008-08-29
• Entrez gene record
  100189174
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34538
• Gene
  TRH-GTG1-5
• Long gene name
  tRNA-His (anticodon GTG) 1-5
• Synonyms gene
  • TRNAH3
  • TRH-GTG1-8
• Synonyms gene name
  • transfer RNA histidine 3 (anticodon GUG)
  • transfer RNA-His (GTG) 1-8
  • transfer RNA-His (GTG) 1-5
• Synonyms
  • tRNA-His-GTG-1-5
• GenBank acession
  • HG983839
• Locus
  6p22.1
• Discovery year
  2008-09-03
• Entrez gene record
  100188987
• Classification
  • Cytoplasmic transfer RNAs

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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