PSMD6 Antibody, ALEXA FLUOR 594
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Catalog numberbs-9367R-A594
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PricePlease ask
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Size100ul
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Long namePSMD6 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
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Also known asAnti-PSMD6 PAb ALEXA FLUOR 594
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CategoryConjugated Primary Antibodies
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Conjugated withALEXA FLUOR® 594
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenPSMD6
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SpecificityThis is a highly specific antibody against PSMD6.
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ModificationUnmodified
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Modification SiteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PSMD6/Proteasome regulatory particle subunit p44S10
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Gene ID Number9861
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigenIn eukaryotic cells, selective breakdown of cellular proteins is ensured by two distinct pathways, ubiquitination and degradation by the 26S proteasome. At specific stages of development, embryo- and tissue-specific components of the 26S proteasome are formed by developmentally regulated alternative splicing, including Rpn10a through Rpn10e (also designated pUb-R2 through pUb-R5). The pUb-R2 subunit, originally identified as S5a, is ubiquitously expressed and may perform proteolysis constitutively in a wide variety of cells. p44S10 is a highly conserved proteasome regulatory subunit that is expressed in heart, liver, skeletal muscle and pancreas. In addition to normal tissue expression, p44S10 is also expressed in several melanoma cell lines, such as MCF-7, 451Lu and WM164. Since forced expression of p44S10 in radial growth phase melanoma cells results in an increase in cellular proliferation, p44S10 may represent a potential link between regulation of proteasome activity and tumor cell proliferation in vivo.
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PurificationPurified by Protein A.
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Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission590nm/617nm
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Synonyms26S proteasome non-ATPase regulatory subunit 6; 26S proteasome regulatory subunit RPN7; 26S proteasome regulatory subunit S10; Breast cancer-associated protein SGA-113M; KIAA0107; p42A; P44S10; PFAAP4; PSMD6_HUMAN; Phosphonoformate immuno-associated protein 4; Proteasome prosome, macropain 26S subunit, non-ATPase, 6; Proteasome regulatory particle subunit p44S10; Rpn7; S10 antibody SGA-113M.
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PropertiesFor facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugationAlexa Fluor, ALEXA FLUOR® 594
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ConjugatedAlexa conjugate 1
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French translationanticorps
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Gene target
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Gene symbolPSMD6-AS2, PSMD6-AS1, PSMD6
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Short nameAnti-PSMD6
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 594
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Alternative namePSMD6 Polyclonal Antibody, ALEXA FLUOR 594
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Alternative techniqueantibodies
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Alternative to gene targetproteasome (prosome, macropain) 26S subunit, non-ATPase, 6, p42A and p44S10 and Rpn7 and S10 and SGA-113M, PSMD6 and IDBG-43018 and ENSG00000163636 and 9861, ATPase activity, nuclei, Psmd6 and IDBG-132715 and ENSMUSG00000021737 and 66413, BT.88479 and IDBG-645134 and ENSBTAG00000015112 and 538625
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Gene info
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Identity
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Gene
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Long gene namePSMD6 antisense RNA 2
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Synonyms gene name
- PSMD6 antisense RNA 2 (non-protein coding)
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GenBank acession
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Locus
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Discovery year2012-06-23
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Entrez gene record
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RefSeq identity
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namePSMD6 antisense RNA 1
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Synonyms
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Locus
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Discovery year2017-01-06
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Pubmed identfication
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameproteasome 26S subunit, non-ATPase 6
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Synonyms gene name
- proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
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Synonyms
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GenBank acession
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Locus
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Discovery year1995-12-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Proteasome
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data