Prokineticin-2, Human Recombinant

• Catalog number
  P1006-20
• Price
  Please ask
• Size
  20 ug

• Synonyms
  PK2, Protein Bv8 homolog, PROK2
• Alternative_names
  PK2, Protein Bv8 homolog, PROK2
• Description
  A cysteine-rich secreted protein that function as an output molecule from the suprachiasmatic nucleus (SCN).
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 1 EU/ug
• Molecular Weight
  8.8 kDa
• Storage Temp
  -20°C
• Shipping
  Gel pack
• Shelf Life
  12 months
• Appearance
  Dry powder
• Physical form description
  Lyophilized powder
• Reconstitution Instructions
  Reconstitute in sterile deionized water to a concentration of 0.1-1.0 mg/ml
• Background Information
  Prokineticin-2 (PK2) is a cysteine-rich secreted protein that is expressed in the testis and, in lower levels, in the small intestine. May function as an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm. May also function locally within the SCN to synchronize output. Potently contracts gastrointestinal (GI) smooth muscle.
• Amino acid sequence
  AVITGACDK DSQCGGGMC CAVSIWVKS IRICTPMGK LGDSCHPLT RKVPFFGRR MHHTCPCLP GLACLRTSF NRFICLAQK
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Prokineticin-2  
• Gene symbol
  PROK2, PROKR2
• Short name
  Prokineticin-2, Recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Prokineticin-2, H. sapiens Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:18455
• Gene
  PROK2
• Long gene name
  prokineticin 2
• Synonyms
  • PK2
  • BV8
  • MIT1
  • KAL4
• Synonyms name
  • protein Bv8 homolog
• GenBank acession
  • AF333025
• Locus
  3p13
• Discovery year
  2002-07-22
• Entrez gene record
  60675
• Pubmed identfication
  • 11054548
  • 11259612
• RefSeq identity
  • NM_001126128
• Classification
  • Receptor ligands
• VEGA ID
  OTTHUMG00000158809

Gene info

• Identity
  HGNC:15836
• Gene
  PROKR2
• Long gene name
  prokineticin receptor 2
• Synonyms gene
  • GPR73L1
  • KAL3
• Synonyms gene name
  • G protein-coupled receptor 73-like 1
  • Kallmann syndrome 3 (autosomal dominant)
• Synonyms
  • GPR73b
  • PKR2
  • GPRg2
  • dJ680N4.3
• GenBank acession
  • AL121755
• Locus
  20p12.3
• Discovery year
  2001-09-17
• Entrez gene record
  128674
• Pubmed identfication
  • 11886876
  • 17054399
• RefSeq identity
  • NM_144773
• Classification
  • Prokineticin receptors
• VEGA ID
  OTTHUMG00000031800

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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