PRKAA1 (167CT22.1.6) Monoclonal Antibody
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Catalog number
bsm-51040M
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Price
Please ask
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Size
0.1ml
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Long name
PRKAA1 (167CT22.1.6) Monoclonal Antibody
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Also known as
PRKAA1 (167CT22.1.6) Monoclonal Antibody
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Category
Primary Antibodies
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Conjugation
Unconjugated
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Target Antigen
PRKAA1
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Specificity
This is a highly specific antibody against PRKAA1.
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Modification s
None
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Modification site s
Unmodified antibody
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Clonality
Monoclonal
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Clone number
167CT22.1.6
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Source
This PRKAA1 Monoclonal antibody was raised using purified His-tagged recombinant human PRKAA1.
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Gene ID number
5562
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Swiss Prot
Q13131
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Tested Applications
WB, IHC-P
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Recommended dilutions
WB(1:1000), IHC-P(1:50~100),
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Cross reactivity
Human
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigen
Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.
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Purification method
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym names
AMPK; AMPKa1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1; PRKAA1; AMPK1
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Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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French translation
anticorps
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Gene target
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Gene symbol
PRKAA1
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Short name
Anti-PRKAA1
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Technique
Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
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Host
Mouse (Mus musculus)
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Isotype
Immunoglobulin G (IgG)1 κ
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Alternative name
PRKAA1 (167CT22.1.6) Monoclonal Antibody
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Alternative technique
antibodies
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Alternative to gene target
protein kinase, AMP-activated, alpha 1 catalytic subunit, AMPK and AMPKa1, PRKAA1 and IDBG-18226 and ENSG00000132356 and 5562, transferase activity, nuclei, Prkaa1 and IDBG-128002 and ENSMUSG00000050697 and 105787, PRKAA1 and IDBG-629895 and ENSBTAG00000000013 and 540404
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Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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