PRIMA 1 for cell activation

PRIMA 1 for cell activation is available 2 times from Biovision labs

2170-5 | PRIMA-1 for cell activationsize: 5 mg | 171.5 USD

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2170-25 | PRIMA-1 for cell activationsize: 25 mg | 448.46 USD

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  • Description
    A small molecule that restores tumor suppressor function to mutant p53 proteins. PRIMA-1 acts as an inducer of apoptosis and inhibitor of growth of human tumors with mutant p53. PRIMA-1 restores sequence-specific DNA binding and transactivational activity to mutant p53 proteins at relatively high µM to mM concentrations.
  • Peptide sequence
    N/A
  • CAS number
    5608-24-2
  • Molecular weight
    185.22
  • Category
    Biochemicals
  • Other name
    2,​2-​bis(hydroxymethyl)-​3-​quinuclidinone
  • Molecular formula
    C₉H₁₅NO₃
  • Physical appearance
    White solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥95%
  • Reconstitute instructions
    H₂O (100 mM)
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    24months
  • Storage instructions
    Protect from air and moisture
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    PRIMA-1 for activation
  • Technique
    activation
  • Alternative name
    PRIMA-1 to measure cellular activation
  • Tissue
    cell
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