PP2A alpha + beta Antibody, ALEXA FLUOR 555

• Catalog number
  bs-0029R-A555
• Price
  Please ask
• Size
  100ul

• Long name
  PP2A alpha + beta Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
• Also known as
  Anti-PP2A alpha + beta PAb ALEXA FLUOR 555
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 555
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  PP2A alpha + beta
• Specificity
  This is a highly specific antibody against PP2A alpha + beta.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  267-309/309
• Subcellular location
  Cytoplasm, Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PP-2A
• Gene ID Number
  5515
• Swiss Prot
  P67775
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV4 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  553nm/568nm
• Synonyms
  RP-C; PP2Ac; PP2CA; PP2Calpha; Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha; Replication protein C; PPP2CA
• Properties
  For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 555
• Description
  The Anti-PP2A alpha + beta is a α- or alpha protein sometimes glycoprotein present in blood.
• French translation
  anticorps

• Gene target
  PP2A   alpha   beta  
• Gene symbol
  PPP2R1B, PPP2R1A
• Short name
  Anti-PP2A alpha + beta
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 555
• Alternative name
  PP2A alpha + beta Polyclonal Antibody, ALEXA FLUOR 555
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9303
• Gene
  PPP2R1B
• Long gene name
  protein phosphatase 2 scaffold subunit Abeta
• Synonyms gene name
  • protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform
  • protein phosphatase 2 regulatory subunit A, beta
• Synonyms
  • PR65B
  • PP2A-Abeta
• Synonyms name
  • PP2A-A-beta
  • protein phosphatase 2A, regulatory subunit A, beta isoform
• GenBank acession
  • AF087438
• Locus
  11q23.1
• Discovery year
  1993-01-25
• Entrez gene record
  5519
• Pubmed identfication
  • 2159327
  • 9795170
• RefSeq identity
  • NM_002716
• Classification
  • STRIPAK complex
  • Protein phosphatase 2 scaffold subunits
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000166741

Gene info

• Identity
  HGNC:9302
• Gene
  PPP2R1A
• Long gene name
  protein phosphatase 2 scaffold subunit Aalpha
• Synonyms gene name
  • protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
• Synonyms
  • PR65A
  • PP2A-Aalpha
  • PP2AA
• Synonyms name
  • protein phosphatase 2A, regulatory subunit A, alpha isoform
  • protein phosphatase 2, 65kDa regulatory subunit A
  • protein phosphatase 2A structural subunit A, alpha isoform
• Locus
  19q13.41
• Discovery year
  1993-01-25
• Entrez gene record
  5518
• RefSeq identity
  • NM_014225
• Classification
  • STRIPAK complex
  • Protein phosphatase 2 scaffold subunits
  • Armadillo like helical domain containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000137367

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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