PPARG Antibody

• Catalog number
  F49368-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  PPARG
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, FACS, ELISA
• Recommended dilutions
  Western blot: 1:1000,Flow Cytometry: 1:10-1:50
• Notes
  Titration of the PPARG antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This PPARG antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P37231
• Purity
  Antigen affinity
• Description
  PPARG is a nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses. Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of ARNTL/BMAL1 in the blood vessels (By similarity). [UniProt]
• Immunogen
  A portion of amino acids 1-30 from the human protein was used as the immunogen for this PPARG antibody.
• Storage
  Aliquot the PPARG antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PPARG  
• Gene symbol
  PPARG
• Short name
  Anti-PPARG
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to PPARG
• Alternative technique
  antibodies
• Alternative to gene target
  peroxisome proliferator-activated receptor gamma, CIMT1 and GLM1 and NR1C3 and PPARG1 and PPARG2 and PPARgamma, PPARG and IDBG-18954 and ENSG00000132170 and 5468, arachidonic acid binding, nuclei, Pparg and IDBG-179253 and ENSMUSG00000000440 and 19016, PPARG and IDBG-646391 and ENSBTAG00000001333 and 281993

Gene info

• Identity
  HGNC:9236
• Gene
  PPARG
• Long gene name
  peroxisome proliferator activated receptor gamma
• Synonyms gene name
  • peroxisome proliferative activated receptor, gamma
  • peroxisome proliferator-activated receptor gamma
• Synonyms
  • PPARG1
  • PPARG2
  • NR1C3
  • PPARgamma
• GenBank acession
  • X90563
• Locus
  3p25.2
• Discovery year
  1996-03-12
• Entrez gene record
  5468
• Pubmed identfication
  • 7862171
  • 9750197
• RefSeq identity
  • NM_005037
• Classification
  • Peroxisome proliferator activated receptors
• VEGA ID
  OTTHUMG00000129764

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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