PPAPDC3 Antibody

• Catalog number
  bs-6918R
• Price
  Please ask
• Size
  0.1ml

• Long name
  PPAPDC3 Primary Polyclonal Antibody
• Also known as
  PPAPDC3 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  PPAPDC3
• Specificity
  This is a highly specific antibody against PPAPDC3.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PPAPDC3
• Gene ID number
  84814
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Plays a role as negative regulator of myoblast differentiation, in part through effects on MTOR signaling. Has no detectable enzymatic activity.PPAPDC3, also known as nuclear envelope transmembrane protein 39 (NET39), was initially discovered in an in silico screen for secreted or membrane proteins. It is a member of the PAP2 superfamily of phosphatases and haloperoxidases. PPAPDC3 has recently been shown to act as a negative regulator of myoblast differentiation by diminishing the activity of the mammalian target of rapamycin TOR. PPAPDC3 is highly expressed in cardiac and skeletal muscle and becomes strongly upregulated during cultured myoblast differentiation tissues. Overexpression of PPAPDC3 in myoblasts repressed myogenesis while knockdown by RNA interference promoted differentiation indicating its part in the regulatory mechanism for myogenesis.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  C9orf67; Phosphatidic acid phosphatase type 2 domain-containing protein 3; PPAC3_HUMAN; Ppapdc3; Probable lipid phosphate phosphatase PPAPDC3.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PPAPDC3  
• Gene symbol
  PLPP7
• Short name
  Anti-PPAPDC3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  PPAPDC3 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:28174
• Gene
  PLPP7
• Long gene name
  phospholipid phosphatase 7 (inactive)
• Synonyms gene
  • C9orf67
  • PPAPDC3
• Synonyms gene name
  • chromosome 9 open reading frame 67
  • phosphatidic acid phosphatase type 2 domain containing 3
• Synonyms
  • MGC12921
  • FLJ14662
  • NET39
• Synonyms name
  • nuclear envelope transmembrane protein NET39
• GenBank acession
  • AK027568
• Locus
  9q34.13
• Discovery year
  2004-01-06
• Entrez gene record
  84814
• Pubmed identfication
  • 12958361
• RefSeq identity
  • NM_032728
• Classification
  • Phospholipid phosphatases
• VEGA ID
  OTTHUMG00000020822

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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