CYLN2/CLIP Antibody
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Catalog numberbs-11314R
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PricePlease ask
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Size0.1ml
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Long nameCYLN2/CLIP Primary Polyclonal Antibody
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Also known asCYLN2/CLIP PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenCYLN2/CLIP
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SpecificityThis is a highly specific antibody against CYLN2/CLIP.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CYLN2
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenWilliams Syndrome (WS) is a developmental disorder characterized by cardiovascular problems, dysmorphic features, mental retardation or learning difficulties and several typical behavioral and neurological abnormalities. In Williams Syndrome patients, a heterozygous deletion is present in a region on chromosome 7q11.23 (the Williams Syndrome critical region), which spans approximately 20 genes. This region comprises the CYLN2 gene, which encodes the cytoplasmic linker protein of (CLIP-115). CLIP-115 is a microtubule-binding protein that is abundantly expressed in the brain. Mice with haploinsufficiency for the CYLN2 gene have features similar to that of WS, including mild growth deficiency, brain abnormalities, hippocampal dysfunction and particular deficits in motor coordination.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesCAP GLY domain containing linker protein 2; CAP-Gly domain-containing linker protein 2; CLIP 115; CLIP; CLIP-115; CLIP2; CLIP2_HUMAN; cytoplasmic linker 2; Cytoplasmic linker protein 115; Cytoplasmic linker protein 2; KIAA0291; MGC11333; restin; Similar to RESTIN CYTOPLASMIC LINKER PROTEIN 170 ALPHA 2; WBSCR3; WBSCR4; Williams Beuren syndrome chromosome region 3; Williams Beuren syndrome chromosome region 4; Williams-Beuren syndrome chromosomal region 3 protein; Williams-Beuren syndrome chromosomal region 4 protein; WSCR3; WSCR4.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolCLIP2, CLIP1, CD74, POMC
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Short nameAnti-CYLN2/CLIP
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameCYLN2/CLIP Polyclonal Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameCAP-Gly domain containing linker protein 2
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Synonyms gene
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Synonyms gene name
- cytoplasmic linker 2
- Williams-Beuren syndrome chromosome region 3
- CAP-GLY domain containing linker protein 2
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-09-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameCAP-Gly domain containing linker protein 1
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Synonyms gene
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Synonyms gene name
- restin (Reed-Steinberg cell-expressed intermediate filament-associated protein)
- CAP-GLY domain containing linker protein 1
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Synonyms
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Synonyms name
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Locus
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Discovery year1993-06-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameCD74 molecule
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Synonyms gene
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Synonyms gene name
- CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
- CD74 molecule, major histocompatibility complex, class II invariant chain
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Synonyms
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Synonyms name
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameproopiomelanocortin
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Synonyms
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Synonyms name
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Neuropeptides
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data