PMS2 (PMS2 Postmeiotic Segregation Increased 2, PMS-2, DNA Mismatch Repair Gene Homolog, H_DJ0042M02.9, HNPCC4, PMS1 Protein Homolog 2, PMS2CL, PMSL2)

• Catalog number
  GEN601390
• Price
  Please ask
• Size
  100ug

• Also known as
  PMS2
• Other names
  Pms2; N/A; CG8169 gene product from transcript CG8169-RA; CG8169-PA; Pms2; Pms2-PA; N/A; N/A
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  Pms2; N/A; CG8169; DmelCG8169; dmlh-2; dmlh2; dpms2; Mlh2; pms2; N/A
• Gene name synonims
  Pms2; N/A; CG8169; DmelCG8169; dmlh-2; dmlh2; dpms2; Mlh2; pms2; N/A
• Other gene names
  Pms2; N/A; CG8169; DmelCG8169; dmlh-2; dmlh2; dpms2; Mlh2; pms2; N/A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1
• Clone
  4H231
• Host organism
  Mouse (Mus musculus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes human PMS2. Species Crossreactivity: mouse.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Purified by Protein G chromatography.
• Form Appearance
  Supplied as a liquid in PBS, 0.02% sodium azide.
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested applications
  Western Blot (WB)
• Description
  cDNA genes are a locus (or region) of DNA for functional transcript RNA or protein. An ELISA is used to detect the expressed protein in biological fluids, serum, saliva.

• Gene target
  PMS2   PMS2   Postmeiotic   Segregation   Increased   PMS-2   DNA   Mismatch   Repair   Gene   Homolog   DJ0042M02   HNPCC4   PMS1   Protein   Homolog   PMS2CL   PMSL2  
• Gene symbol
  PMS2, PMS2CL, PMS1, PRKDC, PRB1, HLA-DOA, MIR1289-2, MIR521-2, MIR509-2, MIR512-2
• Short name
  PMS2 (PMS2 Postmeiotic Segregation Increased 2, PMS-2, DNA Mismatch Repair Homolog, H_DJ0042M02 9, HNPCC4, PMS1 Protein Homolog 2, PMS2CL, PMSL2)
• Technique
  dna
• Alternative name
  Anti-PMS2 (PMS2 Postmeiotic Segregation Increased 2, PMS-2, DNA Mismatch Repair Gene Homolog, H_DJ0042M02.9, HNPCC4, PMS1 Protein Homolog 2, PMS2CL, PMSL2)
• Alternative to gene target
  PMS2 postmeiotic segregation increased 2 (S. cerevisiae), HNPCC4 and PMS2CL and PMSL2, PMS2 and IDBG-7921 and ENSG00000122512 and 5395, MutSalpha complex binding, nuclei, Pms2 and IDBG-259679 and ENSMUSG00000079109 and 18861, PMS2 and IDBG-640975 and ENSBTAG00000007364 and 527039

Gene info

• Identity
  HGNC:9122
• Gene
  PMS2
• Long gene name
  PMS1 homolog 2, mismatch repair system component
• Synonyms gene
  • PMSL2
• Synonyms gene name
  • postmeiotic segregation increased (S. cerevisiae) 2
  • PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
  • PMS1 homolog 2, mismatch repair protein
• Synonyms
  • H_DJ0042M02.9
  • HNPCC4
  • MLH4
• Locus
  7p22.1
• Discovery year
  1994-12-13
• Entrez gene record
  5395
• Pubmed identfication
  • 8072530
• RefSeq identity
  • NM_000535
• Classification
  • MutL homologs
• VEGA ID
  OTTHUMG00000023135
• Locus Specific Databases
  • Hereditary Non-Polyposis Colorectal Cancer, HNPCC
  • Global Variome shared LOVD
  • PMS2 database at LOVD-China
  • LRG_161

Gene info

• Identity
  HGNC:30061
• Gene
  PMS2CL
• Long gene name
  PMS2 C-terminal like pseudogene
• Synonyms
  • PMS2P13
• Synonyms name
  • PMS1 homolog 2, mismatch repair system component pseudogene 13
• GenBank acession
  • BC041364
• Locus
  7p22.1
• Discovery year
  2007-11-27
• Entrez gene record
  441194
• Pubmed identfication
  • 15256438
  • 17253626
• RefSeq identity
  • NR_002217
• VEGA ID
  OTTHUMG00000151857

Gene info

• Identity
  HGNC:9121
• Gene
  PMS1
• Long gene name
  PMS1 homolog 1, mismatch repair system component
• Synonyms gene
  • PMSL1
• Synonyms gene name
  • postmeiotic segregation increased (S. cerevisiae) 1
  • PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
• Synonyms
  • MLH2
• Locus
  2q32.2
• Discovery year
  1994-12-13
• Entrez gene record
  5378
• Pubmed identfication
  • 8072530
  • 23608172
• RefSeq identity
  • NM_000534
• Classification
  • MutL homologs
• VEGA ID
  OTTHUMG00000132664
• Locus Specific Databases
  • Hereditary Non-Polyposis Colorectal Cancer, HNPCC
  • Global Variome shared LOVD
  • PMS1 database at LOVD-China
  • LRG_221

Gene info

• Identity
  HGNC:9413
• Gene
  PRKDC
• Long gene name
  protein kinase, DNA-activated, catalytic subunit
• Synonyms gene
  • HYRC
  • HYRC1
• Synonyms gene name
  • protein kinase, DNA-activated, catalytic polypeptide
• Synonyms
  • DNPK1
  • p350
  • DNAPK
  • XRCC7
  • DNA-PKcs
  • DNAPKc
  • DNA-PKC
  • p460
• Synonyms name
  • DNA-dependent protein kinase catalytic subunit
• Locus
  8q11.21
• Discovery year
  1993-11-09
• Entrez gene record
  5591
• Pubmed identfication
  • 7638222
• RefSeq identity
  • NM_001081640
• Classification
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000164239
• Locus Specific Databases
  • LRG_162

Gene info

• Identity
  HGNC:9337
• Gene
  PRB1
• Long gene name
  proline rich protein BstNI subfamily 1
• Synonyms gene name
  • proline rich protein BstNI subfamily 1 (gene/pseudogene)
• Synonyms
  • PM
  • PMF
  • PMS
  • PRB1M
  • PRB1L
• Locus
  12p13.2
• Discovery year
  2001-06-22
• Entrez gene record
  5542
• Pubmed identfication
  • 8317492
• RefSeq identity
  • NM_005039
• Classification
  • Proline rich proteins
• VEGA ID
  OTTHUMG00000157263

Gene info

• Identity
  HGNC:4936
• Gene
  HLA-DOA
• Long gene name
  major histocompatibility complex, class II, DO alpha
• Synonyms gene
  • HLA-DZA
  • HLA-DNA
• Synonyms
  • HLA-D0-alpha
• GenBank acession
  • M31525
• Locus
  6p21.32
• Discovery year
  2001-06-22
• Entrez gene record
  3111
• Pubmed identfication
  • 2370084
• RefSeq identity
  • NM_002119
• Classification
  • C1-set domain containing
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031211
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:35282
• Gene
  MIR1289-2
• Long gene name
  microRNA 1289-2
• Synonyms gene
  • MIRN1289-2
• Synonyms
  • hsa-mir-1289-2
• Locus
  5q31.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302134
• RefSeq identity
  • NR_031621
• Classification
  • MicroRNA MIR1289 family

Gene info

• Identity
  HGNC:32113
• Gene
  MIR521-2
• Long gene name
  microRNA 521-2
• Synonyms gene
  • MIRN521-2
• Synonyms
  • hsa-mir-521-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574481
• RefSeq identity
  • NR_030203
• Classification
  • MicroRNA MIR515 family

Gene info

• Identity
  HGNC:33641
• Gene
  MIR509-2
• Long gene name
  microRNA 509-2
• Synonyms gene
  • MIRN509-2
• Synonyms
  • hsa-mir-509-2
• Locus
  Xq27.3
• Discovery year
  2007-10-24
• Entrez gene record
  100126301
• RefSeq identity
  • NR_030586
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:32091
• Gene
  MIR512-2
• Long gene name
  microRNA 512-2
• Synonyms gene
  • MIRN512-2
• Synonyms
  • hsa-mir-512-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574459
• RefSeq identity
  • NR_030181
• Classification
  • MicroRNA MIR506 family

MeSH Data

• Name
  Targeted Gene Repair
• Concept
  Scope note: A technique which uses synthetic oligonucleotides to direct the cell's inherent DNA repair system to correct a mutation at a specific site in an episome or chromosome.
• Tree numbers
  • E02.095.301.500
  • E05.393.420.301.500
  • E05.393.420.601.575.500
• Qualifiers
  legislation & jurisprudence, ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data

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