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Target antigen
PMP70
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Clonality
Polyclonal antibody
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Clone
Polyclonal antibody
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Raised in
rabbit
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Type of the antibody
IgG polyclonal antibody
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Product form
freeze-dried
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Reacts with species
Mouse. No cross reactivity with other proteins.
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Analyses
WB,IHC-P
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Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human PMP70(646-659aa EFKQITEDTVEFGS), different from the related mouse and rat sequences by one amino acid.
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Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
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Purification
Immunogen affinity purified.
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Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtions
Keep the PMP70 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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Tips
The PMP70 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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Background
ATP-binding cassette sub-family D member 3 is a protein that in humans is encoded by the ABCD3 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette(ABC) transporters. The gene was assigned to human chromosome 1p21-p22 by in situ hybridization. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders.
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Related articles
1. Gartner J, Moser H, Valle D (June 1993). "Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome".Nat Genet 1 (1): 16–23. 2. Gartner J, Kearns W, Rosenberg C, Pearson P, Copeland NG, Gilbert DJ, Jenkins NA, Valle D (April 1993). "Localization of the 70-kDa peroxisomal membrane protein to human 1p21-p22 and mouse 3". Genomics 15 (2): 412–4. 3. "Entrez Gene: ABCD3 ATP-binding cassette, sub-family D (ALD), member 3".
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Gene Name
ABCD3
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Protein Name
ATP-binding cassette sub-family D member 3
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Gene Full Name
ATP-binding cassette, sub-family D(ALD), member 3
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Synonyms
70 kDa peroxisomal membrane protein antibody|ABC 43 antibody|ABC D3 antibody|ABC43 antibody|ABCD 3 antibody|ABCD3 antibody|ABCD3 protein antibody|ABCD3_HUMAN antibody|ATP binding cassette sub family D(ALD) member 3 antibody|ATP binding cassette sub family D member 3 antibody|ATP-binding cassette sub-family D member 3 antibody|Peroxisomal membrane protein 1 antibody|PMP 70 antibody|PMP70 antibody|PXMP 1 antibody|PXMP1 antibody|ZWS2 antibody
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Uniprot ID
P28288
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Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
