PKR Inhibitor

• Catalog number
  P572500
• Price
  Please ask
• Size
  10 mg

• Chemical available in other sizes
  Please inquire size and price
• Stock availability
  Please Inquire
• Cas number
  608512-97-6
• Chemical s molecular weight
  268.29
• Chemical s main applications
  PKR Inhibitor is a drug which acts as a selective inhibitor of the enzyme double-stranded RNA-dependent protein kinase (PKR). It has been shown to effectively inhibit PKR function in vivo and has neuroprotective and nootropic effects in animal studies.
• Chemical s category
  Amines, Aromatics, Heterocycles, Protein Kinase Inhibitors and Activators, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
• Other name
  6,8-Dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one; 6,8-Dihydro-8-(1H-imidazol-4-ylmethylene)- 7H-pyrrolo[2,3-g]benzothiazol-7-one; GW 506033X
• Chemical s formula
  C13H8N4OS
• Physical properties
  No Data Available
• Melting temperature
  No Data Available
• Boiling temperature
  No Data Available
• Chemical s soluble in
  No Data Available
• Stability conditions
  No Data Available
• Storage
  No Data Available
• Chemical s specifications
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  PKR   Inhibitor  
• Gene symbol
  EIF2AK2
• Short name
  PKR Inhibitor
• Alternative name
  PKR suppressor

Gene info

• Identity
  HGNC:9437
• Gene
  EIF2AK2
• Long gene name
  eukaryotic translation initiation factor 2 alpha kinase 2
• Synonyms gene
  • PRKR
• Synonyms gene name
  • protein kinase, interferon-inducible double stranded RNA dependent
• Synonyms
  • PKR
  • EIF2AK1
  • PPP1R83
• Synonyms name
  • protein phosphatase 1, regulatory subunit 83
• GenBank acession
  • BC057805
• Locus
  2p22.2
• Discovery year
  1992-12-04
• Entrez gene record
  5610
• Pubmed identfication
  • 1351683
• RefSeq identity
  • NM_002759
• Classification
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000100962

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