PKR Inhibitor
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Catalog numberP572500
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PricePlease ask
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Size10 mg
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Chemical available in other sizesPlease inquire size and price
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Stock availabilityPlease Inquire
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Cas number608512-97-6
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Chemical s molecular weight268.29
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Chemical s main applicationsPKR Inhibitor is a drug which acts as a selective inhibitor of the enzyme double-stranded RNA-dependent protein kinase (PKR). It has been shown to effectively inhibit PKR function in vivo and has neuroprotective and nootropic effects in animal studies.
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Chemical s categoryAmines, Aromatics, Heterocycles, Protein Kinase Inhibitors and Activators, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
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Other name6,8-Dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one; 6,8-Dihydro-8-(1H-imidazol-4-ylmethylene)- 7H-pyrrolo[2,3-g]benzothiazol-7-one; GW 506033X
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Chemical s formulaC13H8N4OS
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Physical propertiesNo Data Available
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Melting temperatureNo Data Available
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Boiling temperatureNo Data Available
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Chemical s soluble inNo Data Available
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Stability conditionsNo Data Available
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StorageNo Data Available
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DescriptionTissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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Gene target
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Gene symbolEIF2AK2
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Short namePKR Inhibitor
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Alternative namePKR suppressor
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Gene info
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Identity
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Gene
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Long gene nameeukaryotic translation initiation factor 2 alpha kinase 2
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Synonyms gene
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Synonyms gene name
- protein kinase, interferon-inducible double stranded RNA dependent
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1992-12-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Protein phosphatase 1 regulatory subunits
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VEGA ID