Polycystin 1 Antibody

• Catalog number
  bs-2157R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Polycystin 1 Primary Polyclonal Antibody
• Also known as
  Polycystin 1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Polycystin 1
• Specificity
  This is a highly specific antibody against Polycystin 1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  131-180/4303
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Polycystin 1
• Gene ID number
  5310
• Swiss Prot
  P98161
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Involved in renal tubulogenesis. Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Acts as a regulator of cilium length, together with PKD2. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling (By similarity). May be an ion-channel regulator. Involved in adhesive protein-protein and protein-carbohydrate interactions.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  PBP; Pc-1; TRPP1; Polycystin-1; Autosomal dominant polycystic kidney disease 1 protein; PKD1
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Polycystin  
• Gene symbol
  PKD1L1, PKD1, PKD1L3
• Short name
  Anti-Polycystin 1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Polycystin 1 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:18053
• Gene
  PKD1L1
• Long gene name
  polycystin 1 like 1, transient receptor potential channel interacting
• Synonyms gene name
  • polycystic kidney disease 1 like 1
• Synonyms
  • PRO19563
• Synonyms name
  • polycystin-1L1
• GenBank acession
  • AB061683
• Locus
  7p12.3
• Discovery year
  2002-03-21
• Entrez gene record
  168507
• Pubmed identfication
  • 11863367
  • 24336289
• RefSeq identity
  • NM_138295
• VEGA ID
  OTTHUMG00000155649

Gene info

• Identity
  HGNC:9008
• Gene
  PKD1
• Long gene name
  polycystin 1, transient receptor potential channel interacting
• Synonyms gene name
  • polycystic kidney disease 1 (autosomal dominant)
• Synonyms
  • PBP
  • Pc-1
  • TRPP1
• Synonyms name
  • polycystin 1
  • transient receptor potential cation channel, subfamily P, member 1
• GenBank acession
  • L33243
• Locus
  16p13.3
• Discovery year
  2001-06-22
• Entrez gene record
  5310
• Pubmed identfication
  • 19556541
• Classification
  • MicroRNA protein coding host genes
  • C-type lectin domain containing
• VEGA ID
  OTTHUMG00000155795
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:21716
• Gene
  PKD1L3
• Long gene name
  polycystin 1 like 3, transient receptor potential channel interacting
• Synonyms gene name
  • polycystic kidney disease 1-like 3
• GenBank acession
  • AY164485
• Locus
  16q22.2
• Discovery year
  2003-08-05
• Entrez gene record
  342372
• Pubmed identfication
  • 12782129
  • 20538909
• RefSeq identity
  • NM_181536
• Classification
  • C-type lectin domain containing
• VEGA ID
  OTTHUMG00000166114

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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