PKC Gamma (Protein kinase C gamma) Antibody
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Catalog number
bs-50511R
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Price
Please ask
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Size
0.1ml
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Long name
PKC Gamma (Protein kinase C gamma) Primary Polyclonal Antibody
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Also known as
PKC Gamma (Protein kinase C gamma) PAb
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Category
Primary Antibodies
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Conjugation
Unconjugated
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Target Antigen
PKC Gamma (Protein kinase C gamma)
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Specificity
This is a highly specific antibody against PKC Gamma (Protein kinase C gamma) .
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Modification s
None
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Modification site s
Unmodified antibody
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Clonality
Polyclonal antibody
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Clone number
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
Synthetic peptide
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Gene ID number
5582
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Swiss Prot
P05129
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Tested Applications
WB, IP
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Recommended dilutions
WB (0.2 ug/mL) IP (2.0 ug)
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Cross reactivity
Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigen
Protein kinase C (PKC) is a family of serine-threonine kinases that regulate a broad spectrum of cellular functions. The family is composed of nine genes that express structurally related phospholipid-dependent kinases with distinct means of regulation and tissue distribution. Based on their structures and sensitivities to Ca2+ and diacylglycerol (DAG), they have been classified into conventional PKCs (alpha, beta, and gamma), novel PKCs (Delta, Epsilon, Eta, and IPA), and atypical PKCs (Zeta and Lambda/Iota). PKC Gamma is a member of the cPKC subfamily which is activated by Ca2+ and diacylglycerol in the presence of phosphatidylserine. Physiologically, PKC Gamma is activated by a mechanism coupled with receptor-mediated breakdown of inositol phospholipid as other cPKC isotypes. PKC Gamma is expressed solely in the brain and spinal cord and its localization is restricted to neurons. Within the brain, PKC Gamma is the most abundant in the cerebellum, hippocampus and cerebral cortex, where the existence of neuronal plasticity has been demonstrated.
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Purification method
This antibody was purified via Protein A.
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Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym names
PKCC; PKCG; SCA14; PKC-gamma; Protein kinase C gamma type; PRKCG
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Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
PRKCH, PRKD1, PRRT2, PRKDC
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Short name
Anti-PKC Gamma (Protein kinase C gamma)
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Technique
Antibody, antibodies against human proteins, antibodies for
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Host
Rabbit (Oryctolagus cuniculus)
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Isotype
Immunoglobulin G (IgG)
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Alternative name
PKC Gamma (Protein kinase C gamma) Polyclonal Antibody
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Alternative technique
antibodies
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Gene info
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Identity
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Gene
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Long gene name
protein kinase C eta
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Synonyms gene
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Synonyms gene name
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Synonyms
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GenBank acession
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Locus
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Discovery year
1992-06-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- C2 domain containing protein kinases
- AGC family kinases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
protein kinase D1
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Synonyms gene
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Synonyms gene name
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Synonyms
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Locus
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Discovery year
1994-05-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Pleckstrin homology domain containing
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VEGA ID
Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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