PKC alpha/beta/gamma Antibody

  • Catalog number
    bs-3531R
  • Price
    Please ask
  • Size
    0.1ml
  • Long name
    PKC alpha/beta/gamma Primary Polyclonal Antibody
  • Also known as
    PKC alpha/beta/gamma PAb
  • Category
    Primary Antibodies
  • Conjugation
    Unconjugated
  • Target Antigen
    PKC alpha/beta/gamma
  • Specificity
    This is a highly specific antibody against PKC alpha/beta/gamma.
  • Modification s
    None
  • Modification site s
    Unmodified antibody
  • Clonality
    Polyclonal antibody
  • Clone number
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Immunogen range
    180-237/672
  • Subcellular location
    Cytoplasm, Nucleus, Mitochondrion, Cell membrane
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PKC alpha
  • Gene ID number
    5578
  • Swiss Prot
    P17252
  • Tested Applications
    WB, IHC-P, IF(IHC-P)
  • Recommended dilutions
    WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
  • Cross reactivity
    Human, Mouse, Rat, Dog
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the target antigen
    Protein Kinase c alpha (PKC alpha) is an 77 kDa member of the conventional group (cPKCs: sensitive to calcium, diacylglycerol, phosphatidylserine and phorbol esters) of the PKC family of serine/ threonine kinases that are involved in a wide range of physiological processes including mitogenesis, cell survival and transcriptional regulation. PKC alpha is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of a broad range of cellular functions including proliferation, differentiation, development, migration, cell cell adhesion, cell extracellular matrix adhesion, and solute transport. The activation loop threonine (threonine 497 in PKC alpha) of conventional PKCs is phosphorylated by phosphoinositide dependent kinase 1 (PDK1). This phosphorylation is necessary for the autophosphorylation of threonine 638 in the carboxy terminus of PKC alpha, a step that is critical for regulating the rate of PKC alpha dephosphorylation and inactivation.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
  • Synonym names
    AAG6; PKCA; PRKACA; PKC-alpha; Protein kinase C alpha type; PKC-A; PRKCA
  • Description
    The Anti-PKC alpha/beta/gamma is a α- or alpha protein sometimes glycoprotein present in blood.
  • Properties
    If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    PRKCH, PRKD1, PRRT2, PRKDC
  • Short name
    Anti-PKC alpha/beta/gamma
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Host
    Rabbit (Oryctolagus cuniculus)
  • Isotype
    Immunoglobulin G (IgG)
  • Alternative name
    PKC alpha/beta/gamma Polyclonal Antibody
  • Alternative technique
    antibodies
Gene info
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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