Pin1 (Ser16) Antibody

• Catalog number
  bs-3354R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Pin1 (Ser16) Primary Polyclonal Antibody
• Also known as
  Pin1 (Ser16) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Pin1 Ser16
• Specificity
  This is a highly specific antibody against Pin1 Ser16. This phosphorylation site is homologous across the listed species.
• Modification s
  Phosphorylation
• Modification site s
  Ser16
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  1-50/163
• Subcellular location
  Cytoplasm, Nucleus
• Source
  KLH conjugated synthetic phosphopeptide derived from human Pin1 around the phosphorylation site of Ser16
• Gene ID number
  5300
• Swiss Prot
  Q13526
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation. Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  DOD; UBL5; Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; Peptidyl-prolyl cis-trans isomerase Pin1; PPIase Pin1; Rotamase Pin1; PIN1
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Pin1   Ser16  
• Short name
  Anti-Pin1 Ser16
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Pin1 (Ser16) Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  peptidylprolyl cis/trans isomerase, NIMA-interacting 1, DOD and UBL5, PIN1 and IDBG-26087 and ENSG00000127445 and 5300, phosphothreonine binding, nuclei, PIN1 and IDBG-643081 and ENSBTAG00000016988 and 535470

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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