LAT (Tyr161) Antibody
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Catalog numberbs-10127R
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PricePlease ask
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Size0.1ml
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Long nameLAT (Tyr161) Primary Polyclonal Antibody
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Also known asLAT (Tyr161) PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenLAT Tyr161
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SpecificityThis is a highly specific antibody against LAT Tyr161.
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Modification sPhosphorylation
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Modification site sTyr161
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range145-195/262
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Subcellular locationCytoplasm
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SourceKLH conjugated synthetic phosphopeptide derived from human LAT around the phosphorylation site of Tyr161
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Gene ID number27040
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Swiss ProtO43561
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenRequired for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesLAT1; pp36; Linker for activation of T-cells family member 1; 36 kDa phospho-tyrosine adapter protein; p36-38; LAT
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolLAT, SLC7A6, SLC7A7, SPNS1
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Short nameAnti-LAT Tyr161
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameLAT (Tyr161) Polyclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targetlinker for activation of T cells, LAT and IDBG-239499 and ENSG00000213658 and 27040, protein kinase binding, Cell surfaces, Lat and IDBG-209436 and ENSMUSG00000030742 and 16797, BT.26847 and IDBG-638875 and ENSBTAG00000021249 and 514735
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Gene info
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Identity
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Gene
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Long gene namelinker for activation of T cells
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-07-12
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Pubmed identfication
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesolute carrier family 7 member 6
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Synonyms gene name
- solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-01-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Solute carriers
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesolute carrier family 7 member 7
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Synonyms gene
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Synonyms gene name
- solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-01-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Solute carriers
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namesphingolipid transporter 1 (putative)
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Synonyms gene name
- spinster homolog 1 (Drosophila)
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-04-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Solute carriers
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data