LAT (Tyr161) Antibody

• Catalog number
  bs-10127R
• Price
  Please ask
• Size
  0.1ml

• Long name
  LAT (Tyr161) Primary Polyclonal Antibody
• Also known as
  LAT (Tyr161) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  LAT Tyr161
• Specificity
  This is a highly specific antibody against LAT Tyr161.
• Modification s
  Phosphorylation
• Modification site s
  Tyr161
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  145-195/262
• Subcellular location
  Cytoplasm
• Source
  KLH conjugated synthetic phosphopeptide derived from human LAT around the phosphorylation site of Tyr161
• Gene ID number
  27040
• Swiss Prot
  O43561
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  LAT1; pp36; Linker for activation of T-cells family member 1; 36 kDa phospho-tyrosine adapter protein; p36-38; LAT
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  LAT   Tyr161  
• Gene symbol
  LAT, SLC7A6, SLC7A7, SPNS1
• Short name
  Anti-LAT Tyr161
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  LAT (Tyr161) Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  linker for activation of T cells, LAT and IDBG-239499 and ENSG00000213658 and 27040, protein kinase binding, Cell surfaces, Lat and IDBG-209436 and ENSMUSG00000030742 and 16797, BT.26847 and IDBG-638875 and ENSBTAG00000021249 and 514735

Gene info

• Identity
  HGNC:18874
• Gene
  LAT
• Long gene name
  linker for activation of T cells
• Synonyms
  • LAT1
• Synonyms name
  • linker for activation of T cells, transmembrane adaptor
• GenBank acession
  • AF036905
• Locus
  16q13
• Discovery year
  2002-07-12
• Pubmed identfication
  • 9489702
• VEGA ID
  OTTHUMG00000131761

Gene info

• Identity
  HGNC:11064
• Gene
  SLC7A6
• Long gene name
  solute carrier family 7 member 6
• Synonyms gene name
  • solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
• Synonyms
  • y+LAT-2
  • KIAA0245
  • LAT3
  • LAT-2
• GenBank acession
  • D87432
• Locus
  16q22.1
• Discovery year
  1999-01-28
• Entrez gene record
  9057
• Pubmed identfication
  • 9878049
• RefSeq identity
  • NM_003983
• Classification
  • Solute carriers
• VEGA ID
  OTTHUMG00000176544

Gene info

• Identity
  HGNC:11065
• Gene
  SLC7A7
• Long gene name
  solute carrier family 7 member 7
• Synonyms gene
  • LPI
• Synonyms gene name
  • solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
• Synonyms
  • y+LAT-1
• GenBank acession
  • AF092032
• Locus
  14q11.2
• Discovery year
  1999-01-28
• Entrez gene record
  9056
• Pubmed identfication
  • 9829974
• RefSeq identity
  • NM_003982
• Classification
  • Solute carriers
• VEGA ID
  OTTHUMG00000028692
• Locus Specific Databases
  • LRG_695

Gene info

• Identity
  HGNC:30621
• Gene
  SPNS1
• Long gene name
  sphingolipid transporter 1 (putative)
• Synonyms gene name
  • spinster homolog 1 (Drosophila)
• Synonyms
  • HSpin1
  • nrs
  • SPINL
  • PP2030
  • SPIN1
  • LAT
  • SLC63A1
• GenBank acession
  • BC006156
• Locus
  16p11.2
• Discovery year
  2007-04-12
• Entrez gene record
  83985
• Pubmed identfication
  • 11340170
  • 12815463
• RefSeq identity
  • NM_032038
• Classification
  • Solute carriers
• VEGA ID
  OTTHUMG00000131762

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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