PICK1 Antibody

• Catalog number
  bs-7898R
• Price
  Please ask
• Size
  0.1ml

• Long name
  PICK1 Primary Polyclonal Antibody
• Also known as
  PICK1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  PICK1
• Specificity
  This is a highly specific antibody against PICK1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  240-275/415
• Subcellular location
  Cytoplasm
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PICK1
• Gene ID number
  9463
• Swiss Prot
  Q9NRD5
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  PICK; PRKCABP; PRKCA-binding protein; Protein interacting with C kinase 1; Protein kinase C-alpha-binding protein; PICK1
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PICK1  
• Gene symbol
  PICK1
• Short name
  Anti-PICK1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  PICK1 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  protein interacting with PRKCA 1, PICK and PRKCABP, PICK1 and IDBG-7244 and ENSG00000100151 and 9463, Arp2/3 complex binding, Cell surfaces, Pick1 and IDBG-161096 and ENSMUSG00000068206 and 102632642,18693, PRKCABP and IDBG-641553 and ENSBTAG00000015268 and 533737

Gene info

• Identity
  HGNC:9394
• Gene
  PICK1
• Long gene name
  protein interacting with PRKCA 1
• Synonyms gene
  • PRKCABP
• Synonyms gene name
  • protein kinase C, alpha binding protein
  • protein interacting with PRKCA
• Synonyms
  • dJ1039K5
  • MGC15204
• GenBank acession
  • AL049654
• Locus
  22q13.1
• Discovery year
  1999-10-19
• Entrez gene record
  9463
• Pubmed identfication
  • 10340301
  • 10591208
• RefSeq identity
  • NM_012407
• Classification
  • AH domain containing
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000151159

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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