Phospho-ASK1 (Ser83) Antibody
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Catalog number
A1241-100
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Price
Please ask
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Size
100 µl
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Antibody Target
MAP3K5
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Target Alternative Name
Mitogen-activated protein kinase kinase kinase 5, Apoptosis signal-regulating kinase 1, MAPK/ERK kinase kinase 5, MEK kinase 5, MEKK 5
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Antibody Type
Polyclonal
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Species Reactivities
Human
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Immunogen Sequence
Synthesized peptide derived from human ASK 1 around the phosphorylation site of S83, (20-100aa)
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Accession
Q99683
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Gene Id
4217
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Appearance
Colorless liquid
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Form
Liquid
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Formulation
In PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
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Purification
Affinity-chromatography using epitope-specific immunogen
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Application
WB, ELISA, IHC
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Positive Control
WB: 293 cells
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Application And Usages
WB 1:500-1:2000; ELISA 1:5000-1:20000; IHC 1:100-1:300
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Description
ASK1 (Apoptosis Signal-regulating Kinase 1) activates two different subgroups of MAPKK, MKK4 and MKK6, which in turn activate c-Jun N-terminal Kinase (JNK) and p38 MAP Kinase. ASK1 is activated by TNFR and Fas through the interaction with members of the TRAF Family and the Fas-associated protein Daxx. Overexpression of ASK1 induces apoptosis. However, a catalytically inactive form of ASK1 has been shown to inhibit TNF-α induced apoptosis.
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Storage Condition
-20°C
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Shipping Condition
gel pack
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Shelf Life
12 months
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Usage
For Research Use Only! Not to be used in humans
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Handling
The antibody solution should be gently mixed before use
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Western Blot Verified
Verified
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Immunocytochemistry Verified
Not Verified
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Immunofluorescence Verified
Not Verified
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Immunoprecipitation Verified
Not Verified
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FACS Verified
Not Verified
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ELISA Verified
Not Verified
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ChIP Verified
Not Verified
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Dot Blot Verified
Not Verified
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Flow Cytometry Verified
Not Verified
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Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
MAP3K5
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Short name
Phospho-ASK1 (Ser83) Antibody
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Rabbit IgG
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Alternative name
phosphorilated-ASK1 (Ser83) (antibody to-)
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Alternative technique
antibodies
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Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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