PF 573228 for cell activation

PF 573228 for cell activation is available 2 times from Biovision labs

2819-50 | PF-573228 for cell activationsize: 50 mg | 681.37 USD

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2819-10 | PF-573228 for cell activationsize: 10 mg | 202.79 USD

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  • Description
    PF-573228 is a potent and selective inhibitor of focal adhesion kinase (FAK) (IC₅₀ = 4 nM). PF-573,228 inhibits FAK phosphorylation on Tyr(397) with an IC₅₀ of 30-100 nM.  Displays 50 - 250-fold selectivity for FAK over other protein kinases. Blocks serum and fibronectin-directed migration and decreases focal adhesion turnover in vitro.
  • Peptide sequence
    N/A
  • CAS number
    869288-64-2
  • Molecular weight
    491.49
  • Category
    Biochemicals
  • Other name
    3,4-Dihydro-6-[[4-[[[3-(methylsulfonyl)phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2(1H)-quinolinone
  • Molecular formula
    C₂₂H₂₀F₃N₅O₃S
  • Physical appearance
    Off-white solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    yes
  • Purification
    ≥98% by HPLC
  • Reconstitute instructions
    DMSO (>40 mg/ml)
  • Storage condition
    -20°C
  • Shipping condition
    Gel Pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and light
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    PF-573228 for activation
  • Technique
    activation
  • Alternative name
    PF-573228 to measure cellular activation
  • Tissue
    cell
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