Dishevelled 2 Antibody

• Catalog number
  A02404-3
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  Dishevelled 2
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human, mouse, rat
• Analyses
  WB
• Immunogen
  A synthetic peptide corresponding to a sequence at the N-terminus of human Dishevelled 2 (35-64aa AERITLGDFKSVLQRPAGAKYFFKSMDQDF), identical to the related mouse sequence.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the Dishevelled 2 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The Dishevelled 2 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  Segment polarity protein dishevelled homolog DVL-2 is a protein that in humans is encoded by the DVL2 gene. This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.
• Related articles
  1. Greco TL, Sussman DJ, Camper SA (January 1997). "Dishevelled-2 maps to human chromosome 17 and distal to Wnt3a and vestigial tail (vt) on mouse chromosome 11". Mamm Genome. 7 (6): 475–6. 2. Hocevar, B A; Mou F; Rennolds J L; Morris S M; Cooper J A; Howe P H (June 2003). "Regulation of the Wnt signaling pathway by disabled-2 (Dab2)". EMBO J. England. 22 (12): 3084–94.
• Gene Name
  DVL2
• Protein Name
  Segment polarity protein dishevelled homolog DVL-2
• Gene Full Name
  dishevelled segment polarity protein 2
• Synonyms
  Dishevelled-2 | Dishevelled2 | DSH homolog 2 | DVL 2 | Dvl2 | O14641
• Uniprot ID
  O14641
• Entrez GeneID
  1856
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Dishevelled  
• Gene symbol
  DVL2, DAAM2, DACT2
• Short name
  Dishevelled 2 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Dishevelled 2 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3086
• Gene
  DVL2
• Long gene name
  dishevelled segment polarity protein 2
• Synonyms gene name
  • dishevelled 2 (homologous to Drosophila dsh)
  • dishevelled, dsh homolog 2 (Drosophila)
• GenBank acession
  • BC014844
• Locus
  17p13.1
• Discovery year
  1996-03-12
• Entrez gene record
  1856
• Pubmed identfication
  • 8662242
• RefSeq identity
  • NM_004422
• Classification
  • PDZ domain containing
  • Dishevelled segment polarity proteins
• VEGA ID
  OTTHUMG00000102155

Gene info

• Identity
  HGNC:18143
• Gene
  DAAM2
• Long gene name
  dishevelled associated activator of morphogenesis 2
• Synonyms
  • KIAA0381
• GenBank acession
  • AB002379
• Locus
  6p21.2
• Discovery year
  2002-02-06
• Entrez gene record
  23500
• Pubmed identfication
  • 11779461
  • 12632087
• Classification
  • Formins
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000014653

Gene info

• Identity
  HGNC:21231
• Gene
  DACT2
• Long gene name
  dishevelled binding antagonist of beta catenin 2
• Synonyms gene
  • C6orf116
• Synonyms gene name
  • chromosome 6 open reading frame 116
  • dapper homolog 2, antagonist of beta-catenin (xenopus)
  • dapper, antagonist of beta-catenin, homolog 2 (Xenopus laevis)
• Synonyms
  • bA503C24.7
  • DAPPER2
• GenBank acession
  • AF318336
• Locus
  6q27
• Discovery year
  2003-05-29
• Entrez gene record
  168002
• Classification
  • dishevelled binding antagonist of beta catenin family
• VEGA ID
  OTTHUMG00000016046

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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