PEN2 Antibody, Biotin Conjugated

• Catalog number
  bs-6456R-Biotin
• Price
  Please ask
• Size
  0.1ml

• Long name
  PEN2 Polyclonal Antibody, Biotin Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Biotin
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  PEN2
• Specificity
  This is a highly specific antibody against PEN2. Belongs to the PEN-2 family
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  1-50/101
• Subcellular location
  Lumenal
• Source
  KLH conjugated synthetic peptide derived from human PEN2
• Gene ID number
  55851
• Swiss Prot
  Q9NZ42
• Tested applications
  IHC-P
• Recommended dilutions
  IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  PEN2; PEN-2; MDS033; MSTP064; Gamma-secretase subunit PEN-2; Presenilin enhancer protein 2; PSENEN
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Additional conjugation
  Biotinylated
• French translation
  anticorps

• Gene target
  PEN2   Conjugated  
• Gene symbol
  PSENEN
• Short name
  Anti-PEN2
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Biotin
• Alternative name
  Anti-PEN2 PAb Biotin
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:30100
• Gene
  PSENEN
• Long gene name
  presenilin enhancer, gamma-secretase subunit
• Synonyms gene name
  • presenilin enhancer 2 homolog (C. elegans)
• Synonyms
  • PEN2
• GenBank acession
  • AF220053
• Locus
  19q13.12
• Discovery year
  2005-02-08
• Entrez gene record
  55851
• Pubmed identfication
  • 12110170
  • 12660785
• RefSeq identity
  • NM_172341
• VEGA ID
  OTTHUMG00000182067
• Locus Specific Databases
  • LRG_222

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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